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BB_ Physiology and Pathophysiology ASCP BOC Question Pool Questions with 100% correct answers
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BB: Physiology and PathophysiologyASCP BOC
A man suffering from gastrointestinal bleeding has received 20 units of Red Blood
Cells in the last 24 hours and is still oozing post-operatively. The following results
were obtained:
PT: 20 seconds
aPTT: 43 seconds
platelet count: 160x10^3/uL
Hemoglobin: 10g/dL
Factor VIII: 85%
What blood product should be administered?
a) Fresh Frozen Plasma
b) Red Blood Cells
✅✅
c) Factor VIII Concentrate
d) Platelets - -A
Transfusion of which of the following is needed to help correct hypofibrinogenemia
due to DIC?
a) Whole Blood
b) Fresh Frozen Plasma
✅✅
c) Cryoprecipitated AHF
d) Platelets - -C
A blood component used in the treatment of hemophilia A is:
a) Factor VIII Concentrate
b) Fresh Frozen Plasma
✅✅
c) Platelets
d) Whole Blood - -A
Which of the following blood components is most appropriate to transfuse to an 8
year old male hemophiliac who is about to undergo minor surgery?
a) Cryoprecipitated AHF
b) Red Blood Cells
✅✅
c) Platelets
d) Factor VIII Concentrate - -D
A unit of Fresh Frozen Plasma was inadvertently thawed and then immediately
refrigerated at 4*C on Monday morning. On Tuesday evening this unit may still be
transfused as a replacement for:
a) all coagulation factors
, b) Factor V
✅✅-D
c) Factor VIII
d) Factor IX -
A newborn demonstrates petechiae, ecchymosis and mucosal bleeding. The
preferred blood component for this infant would be:
a) Red Blood Cells
b) Fresh Frozen Plasma
✅✅
c) Platelets
d) Cryoprecipitated AHF - -C
Which of the following would be the best source of Platelets for transfusion in the
case of alloimmune neonatal thrombocytopenia?
a) father
b) mother
✅✅
c) pooled platelet-rich plasma
d) polycythemic donor - -B
A obstetrical patient has had 3 previous pregnancies. Her first baby was healthy, the
second was jaundiced at birth and required an exchange transfusion, while the third
was stillborn. Which of the following is the most likely cause?
a) ABO incompatibility
b) immune deficiency disease
✅✅
c) congenital spherocytic anemia
d) Rh incompatibility - -D
A specimen of cord blood is submitted to the transfusion service for routine testing.
The following results are obtained:
anti-A, 4+; anti-B, 0; anti-D, 3+; Rh Control, 0; DAT, 2+
It is known that the father is group B, with the genotype of dce/dce. Of the following 4
antibodies, which one is the most likely cause of the positive DAT?
a) anti-A
b) anti-D
✅✅
c) anti-c
d) anti-C - -C
ABO-hemolytic disease of the newborn:
a) usually requires an exchange transfusion
b) most often occurs in first born children
✅✅-D
c) frequently results in stillbirth
d) is usually seen only in the newborn of group O mothers -
Which of the following antigens is most likely to be involved in HDN?
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