BCHM 270 module 3 Questions and Answers 100% Pass Enzymes are globular/fibrous proteins. - Correct Answer ✔️✔️-globular What factor do enzymes catalyze a reaction? - Correct Answer ✔️✔️-103-108 times When enzymes bind to a substrate (reactant) they lower the energy which is needed for the reaction to occur. what is this called? - Correct Answer ✔️✔️-activation energy how is the activation energy lowered by the enzyme? - Correct Answer ✔️✔️-stabilization of the transition state a chemical species that has the highest free energy and lowest concentration of those on the pathway from a substrate to a product - Correct Answer ✔️✔️-transition state an enzyme made by RNA - Correct Answer ✔️✔️-ribozyme The site designed for catalysis - Correct Answer ✔️✔️-active site what is the feature of an enzyme that allows it to only catalyze one type of reaction - Correct Answer ✔️✔️-specificity an inactive enzyme - Correct Answer ✔️✔️-apoenzyme by binding an appropr iate cofactor, what happens to apoenzymes? - Correct Answer✔️✔️-they become activated the initial apoenzyme and its bound cofactor - Correct Answer ✔️✔️-holoenzyme a non -protein molecule that can perform reactions that amino acid cannot - Correct Answer✔️✔️-cofactor metal ions are cofactors. T/F - Correct Answer ✔️✔️-true. inorganic metal ions non-protein, organic molecules that can loosely or tightly bind to an enzyme: - Correct Answer✔️✔️-coenzymes. examples of coenzymes - Correct Answer ✔️✔️-ATP NADH Coenzyme A Define prosthetic groups - Correct Answer ✔️✔️-tightly (covalently) bound coenzymes an active site is normally complimentary to the structure of the substrate or the transition state. T/F - Correct Answer ✔️✔️-true what is an active site comprised of? - Correct Answer ✔️✔️-binding site catalytic site the catalytic site is the region where the enzyme binds and orients the substrate. T/F - Correct Answer ✔️✔️-false. binding site the shape and chemistry of the active site determines: - Correct Answer ✔️✔️-catalytic ability to react to one specific reaction type can more than one interaction occur at an active site? - Correct Answer ✔️✔️-yes. conformational changes occurring to facilitate reaction which enzyme model explains the specificity of the binding o f a substrate, but not the ability for enzymes to be flexible? - Correct Answer ✔️✔️-lock and key model the lock and key model works well for which type of binding? - Correct Answer ✔️✔️-
receptor binding transition state stabilization and enzyme catalysis is explained through the lock and key model. t/f - Correct Answer ✔️✔️-false this model states that the enzyme is flexible. - Correct Answer ✔️✔️-induced fit model. active site continually reshaped by interactions with substrate and enzyme what effect does th e active site have on the substrate and enzyme in the induced fit model? - Correct Answer ✔️✔️-modifies the shape of enzyme, sometimes substrate stabilizes substrate into transition state reaction moves forward enzymes are reversible. t/f - Correct Answer ✔️✔️-true in mammalian cells, one enzyme is typically favored where in other reactions, two enzymes are needed. t/f - Correct Answer ✔️✔️-true define isoenzymes - Correct Answer ✔️✔️-Enzymes which exist in different forms in the body but performs the same fu nction what is unique about isoenzymes - Correct Answer ✔️✔️-they are coded by different genes, but catalyze same reaction isoforms are the same as isoenzymes. t/f - Correct Answer ✔️✔️-false
receptor binding transition state stabilization and enzyme catalysis is explained through the lock and key model. t/f - Correct Answer ✔️✔️-false this model states that the enzyme is flexible. - Correct Answer ✔️✔️-induced fit model. active site continually reshaped by interactions with substrate and enzyme what effect does th e active site have on the substrate and enzyme in the induced fit model? - Correct Answer ✔️✔️-modifies the shape of enzyme, sometimes substrate stabilizes substrate into transition state reaction moves forward enzymes are reversible. t/f - Correct Answer ✔️✔️-true in mammalian cells, one enzyme is typically favored where in other reactions, two enzymes are needed. t/f - Correct Answer ✔️✔️-true define isoenzymes - Correct Answer ✔️✔️-Enzymes which exist in different forms in the body but performs the same fu nction what is unique about isoenzymes - Correct Answer ✔️✔️-they are coded by different genes, but catalyze same reaction isoforms are the same as isoenzymes. t/f - Correct Answer ✔️✔️-false
