Pharmacology Practice Exam II
Ionization of a local anesthetic depends on:
A) Concentration of epinephrine
B) Presence of epinephrine
C) The media pH
D) The media pH and drug pKa
E) B and D are correct - ANS-D
Another application of Lidocaine (systemic) is:
A) Analgesic
B) Antidepressant
C) Antiallergic
D) Antiinflammatory
E) Antiarrhythmic - ANS-E
Potassium channels in the nerve membrane produce ____________ during nerve
conduction
A) Re-polarization
B) Depolarization
C) Contraction
D) Dilation
E) None of the above - ANS-A
Lidocaine is an amide. Procaine is an ester.
A) Only the first statement is correct
B) Only the second statement is correct
C) Both statements are correct
D) Both statements are false - ANS-C
There is a negative charge inside the neurons on resting conditions. Polarization of the
membrane means negative inside and positive outside.
A) Only the first statement is correct
B) Only the second statement is correct
, C) Both statements are correct
D) Both statements are false - ANS-C
An action potential can be described as a wave of membrane depolarizations.
Depolarization occurs when positive charges predominate inside the neuronal
membrane.
A) Only the first statement is correct
B) Only the second statement is correct
C) Both statements are correct
D) Both statements are false - ANS-C
Which of the following agents is a potentially unstable and allergenic local anesthetic?
A) Tetracaine
B) Prilocaine
C) Lidocaine
D) Mepivacaine
E) Articaine - ANS-A
About bupivacaine (Marcaine):
A) It is a general anesthetic
B) It is a local anesthetic with the longest duration of action
C) It is a local anesthetic with the best water solubility
D) All of the above
E) None of the above - ANS-B
The first (i.e., less resistant) function to be lost with a local anesthetic is:
A) Cold
B) Warmth
C) Pain
D) ANS (Autonomic)
E) Motor - ANS-D
Lidocaine targets sodium channels in nerves. Epinephrine targets sodium channels in
vessels.
A) Both statements are correct.
B) Only the first statement is correct
C) Only the second statement is correct
D) Both statements are false - ANS-B
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