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BIOL 473 Final Exam Correctly Answered Rate A+

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SRY transcription factor is only found in what kinds of animals? - Mammals (eutherians, marsupials, but not monotremes) Sry is expressed very transiently by - The pre-Sertoli cells (cells in the genital ridge that are derived from the coelomic epithelium cells) SRY promotes the pre-Sertoli cells to form - testes cords Which transcription factor binds too many of the same targets as Sry? - SOX9 Sry drives the expression of SOX9: true or false - True The SRY sequence is well conserved across animals: true or false - false Nuclear localization signals are well-conserved signals that flank the ends of the HMG box in human and mouse. A mutation is this signal on either side of the HMG box means that the transcription factor cannot get into the nucleus resulting in? - - won't differentiate along the male pathway if you are a XY genotype - XY gender reversal The pattern of expression of SRY is not - conserved In humans, SRY is expressed outside of? - the gonads The seminiferous tubules are vascular or avascular? - A vascular environment Completion of normal development requires? - 1. At least two x chromosomes in females 2. Not more than one X in a testes Gonadal development in people with Turner's Syndrome results in... - streak gonad or gonadal dysplasia Of the three types of kidneys that form during embryonic development, which one remains and which ones degenerate - Metanephros remains

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