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Neural Circuits Lecture 10

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These revision notes delve into the developmental programs that control brain wiring to understand the cues that trigger neurons to take the correct shape and connect with appropriate partners. My revision notes also concisely explore how understanding neural circuit assembly suggests ways of treat...

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  • August 1, 2019
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  • 2018/2019
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Neural Circuits NC 10

Associative learning




Associative learning can be emotional responses involving the amygdala or
skeletal musculature involving the cerebellum

Classical conditioning is a form of learning originally described in dogs by the
Russian scientist Ivan Pavlov

Classical conditioning of Aplysia gill withdrawal (homosynpatic plasticity)
 Unpaired delivery of touch (CS) to
the siphon before training
 Paired delivery of touch and tail
shock (US) during training
 Touch (CS) after training
 This is a form of Heterosynaptic
facilitation
 Increase of the efficacy of
synaptic transmission
between a test interneuron
and a post-synaptic neuron,
produced by the stimulation
of a separate pathway.

Homosynaptic plasticity:
- Changes (facilitation or depression) occur in the same synapse that gets
activated.
Heterosynaptic plasticity:
- A synapse, other than the activated one that gets facilitated (or depressed).

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