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pharm MSK + neuro DOC, indications, PK Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution $7.99   Add to cart

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pharm MSK + neuro DOC, indications, PK Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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pharm MSK + neuro DOC, indications, PK Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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  • June 19, 2024
  • 19
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
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pharm MSK + neuro DOC, indications,
PK
RA DOC
Methotrexate


what to reduce with MTX
renal dosing


what to take folic acid with?
Methotrexate


Methotrexate contraindications
pregnancy
CLD
immunocompromised
bleeding issues


MTX AE
hepatic fibrosis
pneumonitis
stomatitis
leukopenia
thrombocytopenia


Leflumonide PK
3d loading dose to achieve steady state
if AE lower to 10mg/d


Leflumonide contraindications
pregnancy
CLD

,second line for RA
TNF


what to use for RA + pregnancy
hydroxychloroquine


AE of hydroxychloroquine
GI
vison issues


can you combine DMARDS
no


biologic DMARDs
need to monitor?
TB skin test
screen hep B
avoid live vaccines


TNF risks
do NOT use w heart disease
risk of infection, malignancies, demyelinating disorders (MS)


what drug do you premedicate with antihistamine
infliximab


contraindications infliximab
active ifections
CHF


indication for abatacept

, moderate to severe RA
who fail DMARDS


polymalgia rheumatica drug
IL-6 inhibitor


monitor for IL-6 inhibitor
hep B, AST, ALT
ANC + lipids 4-8w + q3months


contraindication IL-6 inhibitor
ALT or AST >1.5 ULN
active infection


what to combine w anti-CD20
methylprednisone
acetaminophen
antihistamine
decreases immune reactions


indications anti-CD20
mod-severe RA only in combo w MTX
Bcell non-hodgkins
CLL/ SLL
pemphigus vulgaris
myasthenia gravis


when is breastfeeding contraindicated
hydroxychloroquine
sulfasalazine
anti-CD20


when is Cr Cl <30 contraindicated

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