The best biology notes for A- level biology : Topic 8
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Course
Paper 2 module
Institution
AQA
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Mutations
mutations canhappen
by errors made during
DNA replication
substitution-bases swapped for another
GCTACC GCAACC
Deletion-bases removed
GCTACC GLACC
Addition-base inserted
GCTACC GCTGACd
Duplication-base repeated
GCTACC GCTTACC
reversed
Inversion-sequence GCTCCA
GCTACC
Translocation-sequence moved from one
place to another
(either on same or
different
chromosome)
↳ mutations can
change the amino
acid coded for and therefore
and
change
structure protein
primary of
potentially change tertiary structure
not all mutations result in
acid due
a
change
of amino
nature DNA code
to
deg enerative
of
meshift
mutations mutagenic agents
-
↳ increase rate of
↳ Mutation
all subsequent triplets ,
affected
as
length of DNA changes Dact as a base
deletion addition and duplication ② bases
altering
,
causes
as more
a
larger impact
&
amno acids
on protein
affected
/ Change
structure
DNA
(make
replication harder)
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