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Clinical Pharmacology Test 1 questions and answers
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Clinical Pharmacology Test 1 questions and answers
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Clinical Pharmacology Test 1A drug has a 20 hour half-life. How long will it take for this drug to be considered "cleared"
from the body?
10 hours
50 hours
100 hours
500 hours - correct answer-100 hours
A drug that increases or speeds up the activity on the enzyme is called what?
Synergistic effects
Enzyme inhibition
Enzyme induction
Antagonistic effects - correct answer-Enzyme induction
A measurement of the amount of drug or dose of drug required to produce a given effect
Antagonist
Agonist
Potency
Efficacy - correct answer-Potency
A measurement of the probability that a drug molecule will interact with a receptor. Describes
the tightness of the bond between a drug and a receptor.
Antagonist
Potency
Selectivity
Affinity - correct answer-Affinity
A patient with a history of angina should receive:
I. daily aspirin
II. clopidogrel (Plavix)
III. dipyridamole + aspirin (Aggrenox)
IV. warfarin (Coumadin)
I only
II only
III only
IV only
Either I, II, or III are appropriate - correct answer-Either I, II, or III are appropriate
A patient with a history of myocardial infarction should receive:
I. daily aspirin
,II. clopidogrel (Plavix)
III. dipyridamole + aspirin (Aggrenox)
IV. warfarin
I. Only
II. Only
III. Only
IV. Only
Either I, II, or III are appropriate - correct answer-Either I, II, or III are appropriate
A patient with a history of peripheral vascular disease (PVD) who is allergic to aspirin should
receive:
Daily aspirin
Warfarin (Coumadin)
Clopidogrel (Plavix) - correct answer-Clopidogrel (Plavix)
A patient with a history of recent deep vein thrombosis (DVT) or pulmonary embolism (PE)
should receive:
Daily aspirin
Warfarin (Coumadin)
Clopidogrel (Plavix) - correct answer-Warfarin (Coumadin)
A patient with a history of recent deep vein thrombosis (DVT) or pulmonary embolism (PE)
should receive?
Daily Aspirin
Warfarin (Coumadin)
Clopidogrel (Plavix) - correct answer-Warfarin (Coumadin)
A patient with a prosthetic heart valves should receive:
Daily aspirin
Warfarin (Coumadin)
Clopidogrel (Plavix) - correct answer-Warfarin (Coumadin)
ACE-Inhibitors are beneficial in CHF because they help to block one of the compensatory
mechanisms involved in worsening heart failure.
True
False - correct answer-True
Antihypertensive of choice in patients with congestive heart failure.
Captopril (Capoten)
Amlodipine (Norvasc)
Doxazosin (Cardura) - correct answer-Captopril (Capoten)
, Antihypertensive of choice in patients with diabetes.
Propranolol (Inderal)
Captopril (Capoten)
Furosemide (Lasix)
Amlodipine (Norvasc) - correct answer-Captopril (Capoten)
Antihypertensive of choice in patients with renal failure and fluid overload (edema).
Lisinopril (Zestril)
Propranolol (Inderal)
Prazosin (Minipress)
Furosemide (Lasix) - correct answer-Furosemide (Lasix)
Associated with orthostatic hypotension & first dose syncope.
Captopril (Capoten)
Prazosin (Minipress)
Atenolol (Tenormin) - correct answer-Prazosin (Minipress)
Blocking of alpha 1 receptors in the vasculature of the skin, mucus membranes, and most
organs will cause what physiologic response?
Vasodilation
Vasoconstriction - correct answer-Vasodilation
Blocking of beta 1 receptors will cause what physiologic response?
Increased heart rate
Decreased heart rate - correct answer-Decreased heart rate
Blocking of Beta 2 receptors in the liver will cause what physiologic response?
Increased liver sugar production
Decreased liver sugar production - correct answer-Decreased liver sugar production
Blocking of beta 2 receptors in the lungs will cause what physiologic response?
Bronchodilation
Bronchoconstriction - correct answer-Bronchoconstriction
Blocking of Beta 2 receptors in the vasculature of the skeletal muscles, lungs, and heart will
cause what physiologic response?
Vasodilation
Vasoconstriction - correct answer-Vasoconstriction
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