NSG 124 Pharmacology Exam 3
What is an ACE Inhibitor? - correct answer-Angiotensin-Converting Enzyme
:Causes vasoconstriction and increased blood pressure
ACE Inhibitors relax heart and decrease blood pressure
What is an examples of a drug ACE Inhibitor? - correct answer-Captopril (Capten)
Benazepril
Perindopril
Trandolapril
Moexipril
what does ACE inhibitors treat? - correct answer-HTN, HF, Diabetic Neuropathy, and MI
What is the function of ACE Inhibitors? - correct answer-Reduce levels of angiotensin II-
Bradykinin (dilate blood vessels), reduce blood volume (kidney excretion), Hyperkalemia
(elevates potassium in blood)
**LOWERS BLOOD PRESSURE**
What are the side effects of ACE inhibitors? - correct answer-Angioedema, cough (causes
from bradykinin), hyperkalemia, hypotension, renal failure
Where is the ACE inhibitors excreted from? - correct answer-Kidneys
What interacts with ACE inhibitors? - correct answer-Diuretics, Antihypertensives, potassium
supplements, lithium, and NSAIDS
What are the adverse effects of ACE inhibitors? - correct answer-Hypotension (<90 SBP);
dry cough; hyperkalemia (potassium 3.5-5) angioedema (deep tissue swelling (face, mouth,
eyes, throat- high risk in african americans); Dizziness in changing positions (orthostatic
hypotension)
what do you monitor while patient is on ACE inhibitors? - correct answer-BP, Potassium
levels (3.5-5), BUN (5-20), creatinine (0.6-1.2), I&O, angioedema (deep tissue swelling (face,
mouth, eyes, throat- mostly seen in african americans)
Education on ACE inhibitors and ARB's - correct answer-BP & pulse regularly
Avoid salt substitutes w/ potassium rich foods (potatoes, bananas, pork, oranges, tomatoes,
avocados, spinach)
Talk to MD if dry cough is not tolerated instead of stopping medication.
Spironolactone with ACE or ARB's can increase potassium in blood.
DO OT double dose when dose is forgotten. Take dose as scheduled next day. Risk of
severe hypotension if doubled.
What are ARB's? - correct answer-Angiotensin II Receptor Blockers
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