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Module 10 - pharmacology.
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Module 10 - pharmacology.
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Module 10 - pharmacologynon pharmacologic anxiety interventions - correct answer-deep breathing, guided imagery,
music, psychotherapy, support groups
-lam, -pam nursing considerations - correct answer-- asses vitals (drugs lower BP + HR),
renal function
- bed alarm
- mostly taken PRN
- assess suicidal thoughts
buspirone indication - correct answer-anxiety
buspirone MOA - correct answer-binds to serotonin + dopamine receptors
buspirone interactions - correct answer-grapefruit juice - toxicity
busprione adverse effects - correct answer-drowsiness, dizziness, headache, nausea,
nervousness, excitement
buspirone nursing considerations - correct answer-- take on a scheduled basis
- may take 1-2 weeks to become fully effective
lithium indications - correct answer-manic episodes in bipolar psychosis
lithium MOA - correct answer-alters ion transport in nerve and muscle cells and increases
receptor sensitivity to serotonin
lithium interactions - correct answer-increased levels with diuretics, methydopa, NSAIDs,
haloperidol, antidepressants, theophylline, phenothiazole
lithium therapeutic range - correct answer-0.5-1.5
lithium adverse effects - correct answer-headache, drowsiness, dizziness, hypotension,
restlessness, slurred speech, metallic taste, dry mouth, GI distress, tremors, muscle
weakness, hand/ankle edema, increased urination, blood dyscarias
lithium toxicity s/s - correct answer-nausea, vomiting, diarrhea, slurred speech, increased
tremors, seizures, coma, decreased coordination
lithium nursing considerations - correct answer-- monitor kidney function
- monitor for low Na (<145)
- suicidal thoughts
- increase fluid intake
- avoid caffeine
- take w food to minimize GI upset
, amitriptyline, nortriptyline indications - correct answer-major/agitated depression
amitriptyline, nortriptyline MOA - correct answer-blocks norepinephrine + serotonin uptake in
the brain + blocks histamine receptors
amitriptyline, nortriptyline contraindications - correct answer-MAOIs (14 days), pregnancy, pt
with chronic cardiac/seizure disorders
amitriptyline, nortriptyline interactions - correct answer-- cns dep. + alcohol - increased cns
effects
- MAOIs - cardiotoxicity
- phenothiazine, haloperidol - increased sedation + anticholinergic effects
amitriptyline, nortriptyline adverse effects - correct answer-sedation, dizziness,
anticholinergic, weight gain, GI distress, sexual dysfunction, orthostatic hypotension,
dysrhythmias, blood dyscarias
amitriptyline, nortriptyline nursing considerations - correct answer-- rise in stages
- take at bed time
isocarboxazid, tranylcypromine,
phenelzine, selegiline (MAO-B, TD patch) indications - correct answer-depression not
controlled by TCAs or 2nd gen antidepressants
isocarboxazid, tranylcypromine,
phenelzine, selegiline (MAO-B, TD patch) MOA - correct answer-blocks MO enzyme that
inactivates norepinephrine, dopamine, epinephrine, and serotonin
isocarboxazid, tranylcypromine,
phenelzine, selegiline (MAO-B, TD patch) interactions - correct answer-- phenylephrine +
pseudo - HTN crisis
- must be off TCA, SSRI, SNRI 14 days before starting med
- tyramine containing foods
tyramine containing foods - correct answer-cheddar, blue, Swiss, sausage, pepperoni,
salami, smoked fish, yeast, red wine, fav a beans
isocarboxazid, tranylcypromine,
phenelzine, selegiline (MAO-B, TD patch) adverse effects - correct answer-agitation,
restlessness, insomnia, anticholinergic, orthostatic hypotension, HTN crisis from fatal
tyramine reaction
fluvoxamine, fluoxetine, sertraline, citalopram indications - correct answer-major depression,
anxiety, OCD, phobias, panic, migraine prevention
fluvoxamine, fluoxetine, sertraline, citalopram MOA - correct answer-block uptake of
serotonin
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