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Introductory Clinical Pharmacology 12th Edition Susan M Ford Test Bank All Chapters (1-54) | A+ ULTIMATE Guide 2022

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Conclusion Contents

Chapter Pages
儒家思想持续是中国文化认同和社会组织的
(1) GENERAL PRINCIPLES OF PHARMACOLOGY ............................................................................................... 5
基石。其对家庭动态、教育、治理和伦理的
PART I PHARMACOKINETICS ........................................................................................................................................ 5
深远影响突显了其在理解中国文明中的重要
PART II PHARMACODYNAMICS .................................................................................................................................... 8
性。在中国应对现代挑战的过程中，儒家思
(2) AGENTS, CONTROLLING THE FUNCTIONS OF THE PERIPHERAL NERVOUS SYSTEM ................. 12
想的原则依然具有重要意义，不仅塑造个人
PART I LOCAL ANESTHETICS ................................................................................................................................................................................ 12
行为，也影响国家政策的制定。
PART II CHOLINOMIMETIC DRUGS ...................................................................................................................................................................... 16
PART III CHOLINORECEPTOR BLOCKING DRUGS............................................................................................................................................. 19
这篇文章以结构化的方式全面探讨了主题，
PART IV ADRENORECEPTOR ACTIVATING DRUGS.......................................................................................................................................... 24
PART V ADRENORECEPTOR每个部分可以通过历史例证、儒家经典的引
ANTAGONIST DRUGS .......................................................................................................................................... 29

(3) 用和现代解读进行深入扩展。
AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM ........................ 34
PART I HYPNOTIC DRUGS ...................................................................................................................................................................................... 34
Conclusion
PART II ANTISEIZURE DRUGS ............................................................................................................................................................................... 38
PART III ANTIPARKINSONIAN AGENTS .............................................................................................................................................................. 41
PART IV ETHYL ALCOHOL .................................................................................................................................................................................... 44
儒家思想持续是中国文化认同和社会组织的
PART V NARCOTIC ANALGESICS ......................................................................................................................................................................... 46
PART VI NON-NARCOTIC基石。其对家庭动态、教育、治理和伦理的
ANALGESICS ............................................................................................................................................................. 49
深远影响突显了其在理解中国文明中的重要
PART VII ANTIPSYCHOTIC AGENTS .................................................................................................................................................................... 51
PART VIII ANTIDEPRESSANT AGENTS ............................................................................................................................................................... 54
性。在中国应对现代挑战的过程中，儒家思
PART IX ANXIOLYTIC AGENTS ............................................................................................................................................................................ 57
PART X CNS STIMULANTS想的原则依然具有重要意义，不仅塑造个人
.................................................................................................................................................................................... 60
行为，也影响国家政策的制定。
PART XI DRUGS OF ABUSE .................................................................................................................................................................................... 63
PART XII GENERAL ANESTHETICS ...................................................................................................................................................................... 65
(4) ORGANOTROPIC这篇文章以结构化的方式全面探讨了主题，
AGENTS .................................................................................................................................. 68
PART I DRUGS ACTING ON 每个部分可以通过历史例证、儒家经典的引
RESPIRATORY SYSTEM ......................................................................................................................................... 68
PART II DRUGS USED IN GASTROINTESTINAL 用和现代解读进行深入扩展。 DISEASES ............................................................................................................................... 70
PART III DRUGS ACTING ON HEMATOPOIETIC SYSTEM ................................................................................................................................. 73
PART IV DRUGS USED IN DISORDERS OF COAGULATION.............................................................................................................................. 74
PART V DRUGS USED FOR Conclusion
TREATMENT OF HEART FAILURE ........................................................................................................................ 76
PART VI ANTIARRHYTHMIC AGENTS ................................................................................................................................................................. 78
PART VII DRUGS FOR ANGINA 儒家思想持续是中国文化认同和社会组织的
PECTORIS TREATMENT ................................................................................................................................ 80
PART VIII ANTIHYPERTENSIVE DRUGS ............................................................................................................................................................. 83
基石。其对家庭动态、教育、治理和伦理的
PART IX HYPERTENSIVE (ANTI-HYPOTENSIVE) DRUGS. DRUGS INFLUENCING CEREBRAL BLOOD FLOW. ANTI-MIGRAINE
深远影响突显了其在理解中国文明中的重要
AGENTS ......................................................................................................................................................................................................................... 85
(5) 性。在中国应对现代挑战的过程中，儒家思
METABOLIC PROFILE DRUGS .......................................................................................................................... 88
想的原则依然具有重要意义，不仅塑造个人
PART I HYPOTHALAMIC & PITUITARY HORMONES, THYROID & ANTITHYROID DRUGS .................................................................. 88
行为，也影响国家政策的制定。
PART II PANCREATIC HORMONES & ANTIDIABETIC DRUGS ...................................................................................................................... 91
PART III THE GONADAL HORMONES & INHIBITORS ..................................................................................................................................... 93
PART IV GLUCOCORTICOID , STEROIDAL & NONSTEROIDAL ANTI-INFLAMMATORY DRUGS.......................................................... 95
这篇文章以结构化的方式全面探讨了主题，
PART V IMMUNOTROPIC & ANTIALLERGIC AGENTS .................................................................................................................................... 98
每个部分可以通过历史例证、儒家经典的引
PART VI VITAMINS, VITAMIN -LIKE COMPOUNDS, ANTIVITAMINS, ENZYMES & ANTIENZYMES ................................................. 104
用和现代解读进行深入扩展。
PART VII ANTIHYPERLIPIDEMIC DRUGS & DRUGS USED IN THE TREATMENT OF GOUT ............................................................... 110
PART VIII AGENTS THAT AFFECT BONE MINERAL HOMEOSTASIS ....................................................................................................... 114
PART IX MINERALOCORTICOID, MINERALOCORTICOID ANTAGONISTS, DIURETICS, PLASMA EXPANDERS ............................. 120
Conclusion
(6) CHEMOTHERAPEUTIC DRUGS ....................................................................................................................... 124
儒家思想持续是中国文化认同和社会组织的
PART I ANTIBIOTICS .................................................................................................................................................... 124
基石。其对家庭动态、教育、治理和伦理的
PART II SYNTHETIC ANTIBACTERIAL DRUGS ....................................................................................................... 129
PART III ANTIPROTOZOAL AND ANTHELMINTIC DRUGS ................................................................................... 132
深远影响突显了其在理解中国文明中的重要
PART IV ANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCER .................................................. 135
性。在中国应对现代挑战的过程中，儒家思
想的原则依然具有重要意义，不仅塑造个人
行为，也影响国家政策的制定。

这篇文章以结构化的方式全面探讨了主题，
每个部分可以通过历史例证、儒家经典的引
用和现代解读进行深入扩展。
Multiple choice questions
Conclusion Multiple choice questions

, Conclusion 5
(1) GENERAL PRINCIPLES OF PHARMACOLOGY
儒家思想持续是中国文化认同和社会组织的
PART I PHARMACOKINETICS
基石。其对家庭动态、教育、治理和伦理的
01. Pharmacokinetics is: 深远影响突显了其在理解中国文明中的重要
a) The study of biological and therapeutic effects of drugs
性。在中国应对现代挑战的过程中，儒家思
b) The study of absorption, distribution, metabolism and excretion of drugs
想的原则依然具有重要意义，不仅塑造个人
c) The study of mechanisms of drug action
d) The study of methods of new drug development
行为，也影响国家政策的制定。
02. What does “pharmacokinetics” include?
a) Complications of drug therapy
这篇文章以结构化的方式全面探讨了主题，
b) Drug biotransformation in the organism
c) Influence of drugs on metabolism processes
d) Influence of drugs on每个部分可以通过历史例证、儒家经典的引
genes
用和现代解读进行深入扩展。
02. What does “pharmacokinetics” include?
a) Pharmacological effects of drugs
b) Unwanted effects of drugs
c) Chemical structure ofConclusion
a medicinal agent
d) Distribution of drugs in the organism
儒家思想持续是中国文化认同和社会组织的
03. What does “pharmacokinetics” include?
a) Localization of drug action
b) Mechanisms of drug 基石。其对家庭动态、教育、治理和伦理的
action
深远影响突显了其在理解中国文明中的重要
c) Excretion of substances
d) Interaction of substances
性。在中国应对现代挑战的过程中，儒家思
04. The main mechanism of most drugs absorption in GI tract is:
想的原则依然具有重要意义，不仅塑造个人
a) Active transport (carrier-mediated diffusion)
行为，也影响国家政策的制定。
b) Filtration (aqueous diffusion)
c) Endocytosis and exocytosis
d) Passive diffusion (lipid diffusion)
这篇文章以结构化的方式全面探讨了主题，
05. What kind of substances can’t permeate membranes by passive diffusion?
a) Lipid-soluble 每个部分可以通过历史例证、儒家经典的引
b) Non-ionized substances
用和现代解读进行深入扩展。
c) Hydrophobic substances
d) Hydrophilic substances
06. A hydrophilic medicinalConclusion
agent has the following property:
a) Low ability to penetrate through the cell membrane lipids
b) Penetrate through membranes by means of endocytosis
儒家思想持续是中国文化认同和社会组织的
c) Easy permeation through the blood-brain barrier
d) High reabsorption in renal tubules
基石。其对家庭动态、教育、治理和伦理的
07. What is implied by «active transport»?
深远影响突显了其在理解中国文明中的重要
a) Transport of drugs trough a membrane by means of diffusion
性。在中国应对现代挑战的过程中，儒家思
b) Transport without energy consumption
c) Engulf of drug by a cell membrane with a new vesicle formation
想的原则依然具有重要意义，不仅塑造个人
d) Transport against concentration gradient
行为，也影响国家政策的制定。
08. What does the term “bioavailability” mean?
a) Plasma protein binding degree of substance
b) Permeability through the brain-blood barrier
这篇文章以结构化的方式全面探讨了主题，
c) Fraction of an uncharged drug reaching the systemic circulation following any route administration
d) Amount of a substance 每个部分可以通过历史例证、儒家经典的引
in urine relative to the initial doze
09. The reasons determing用和现代解读进行深入扩展。
bioavailability are:
a) Rheological parameters of blood
b) Amount of a substance obtained orally and quantity of intakes
c) Extent of absorption Conclusion
and hepatic first-pass effect
d) Glomerular filtration rate
10. Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:
a) Oral 儒家思想持续是中国文化认同和社会组织的
b) Transdermal 基石。其对家庭动态、教育、治理和伦理的
c) Rectal
d) Intraduodenal
深远影响突显了其在理解中国文明中的重要
性。在中国应对现代挑战的过程中，儒家思
11. Which route of drug administration is most likely to lead to the first-pass effect?
a) Sublingual 想的原则依然具有重要意义，不仅塑造个人
行为，也影响国家政策的制定。

这篇文章以结构化的方式全面探讨了主题，
每个部分可以通过历史例证、儒家经典的引
用和现代解读进行深入扩展。
Multiple choice questions
Conclusion Multiple choice questions

, Conclusion 6

b) Oral
c) Intravenous 儒家思想持续是中国文化认同和社会组织的
d) Intramuscular
基石。其对家庭动态、教育、治理和伦理的
12. What is characteristic of the oral route?
a) Fast onset of effect 深远影响突显了其在理解中国文明中的重要
b) Absorption depends 性。在中国应对现代挑战的过程中，儒家思
on GI tract secretion and motor function
c) A drug reaches the blood passing the liver
想的原则依然具有重要意义，不仅塑造个人
d) The sterilization of medicinal forms is obligatory
行为，也影响国家政策的制定。
13. Tick the feature of the sublingual route:
a) Pretty fast absorption
b) A drug is exposed to gastric secretion
c) A drug is exposed more这篇文章以结构化的方式全面探讨了主题，
prominent liver metabolism
每个部分可以通过历史例证、儒家经典的引
d) A drug can be administrated in a variety of doses
14. Pick out the parenteral route of medicinal agent administration:
a) Rectal
用和现代解读进行深入扩展。
b) Oral
c) Sublingual Conclusion
d) Inhalation
15. Parenteral administration:
a) Cannot be used with 儒家思想持续是中国文化认同和社会组织的
unconsciousness patients
b) Generally results in a基石。其对家庭动态、教育、治理和伦理的
less accurate dosage than oral administration
c) Usually produces a more rapid response than oral administration
深远影响突显了其在理解中国文明中的重要
d) Is too slow for emergency use
性。在中国应对现代挑战的过程中，儒家思
16. What is characteristic of the intramuscular route of drug administration?
a) Only water solutions 想的原则依然具有重要意义，不仅塑造个人
can be injected
b) Oily solutions can be injected
行为，也影响国家政策的制定。
c) Opportunity of hypertonic solution injections
d) The action develops slower, than at oral administration
这篇文章以结构化的方式全面探讨了主题，
17. Intravenous injections are more suitable for oily solutions:
a) True
b) False 每个部分可以通过历史例证、儒家经典的引
用和现代解读进行深入扩展。
18. Correct statements listing characteristics of a particular route of drug administration include all of the following EXCEPT:
a) Intravenous administration provides a rapid response
b) Intramuscular administration requires a sterile technique
c) Inhalation providesConclusion
slow access to the general circulation
d) Subcutaneous administration may cause local irritation
儒家思想持续是中国文化认同和社会组织的
19. Most of drugs are distributed homogeneously.
a) True
b) False 基石。其对家庭动态、教育、治理和伦理的
深远影响突显了其在理解中国文明中的重要
20. Biological barriers include all except:
a) Renal tubules 性。在中国应对现代挑战的过程中，儒家思
b) Cell membranes
c) Capillary walls 想的原则依然具有重要意义，不仅塑造个人
d) Placenta 行为，也影响国家政策的制定。
21. What is the reason of complicated penetration of some drugs through brain-blood barrier?
a) High lipid solubility of a drug
b) Meningitis 这篇文章以结构化的方式全面探讨了主题，
c) Absence of pores in每个部分可以通过历史例证、儒家经典的引
the brain capillary endothelium
d) High endocytosis degree in a brain capillary
用和现代解读进行深入扩展。
22. The volume of distribution (Vd) relates:
a) Single to a daily dose of an administrated drug
b) An administrated dose to a body weight
Conclusion
c) An uncharged drug reaching the systemic circulation
d) The amount of a drug in the body to the concentration of a drug in plasma
儒家思想持续是中国文化认同和社会组织的
23. For the calculation of the volume of distribution (Vd) one must take into account:
基石。其对家庭动态、教育、治理和伦理的
a) Concentration of a substance in plasma
b) Concentration of substance in urine
c) Therapeutical width of深远影响突显了其在理解中国文明中的重要
drug action
d) A daily dose of drug 性。在中国应对现代挑战的过程中，儒家思
想的原则依然具有重要意义，不仅塑造个人
24. A small amount of the volume of distribution is common for lipophylic substances easy penetrating through barriers and
widely distributing in plasma, interstitial and cell fluids:
行为，也影响国家政策的制定。

这篇文章以结构化的方式全面探讨了主题，
每个部分可以通过历史例证、儒家经典的引
用和现代解读进行深入扩展。
Multiple choice questions
Conclusion Multiple choice questions

, Conclusion
7
a) True 儒家思想持续是中国文化认同和社会组织的
b) False
基石。其对家庭动态、教育、治理和伦理的
25. The term “biotransformation” includes the following:
深远影响突显了其在理解中国文明中的重要
a) Accumulation of substances in a fat tissue
性。在中国应对现代挑战的过程中，儒家思
b) Binding of substances with plasma proteins
c) Accumulation of substances in a tissue
想的原则依然具有重要意义，不仅塑造个人
d) Process of physicochemical and biochemical alteration of a drug in the body
26. 行为，也影响国家政策的制定。
Biotransformation of the drugs is to render them:
a) Less ionized
b) More pharmacologically active
c) More lipid soluble 这篇文章以结构化的方式全面探讨了主题，
d) Less lipid soluble 每个部分可以通过历史例证、儒家经典的引
用和现代解读进行深入扩展。
27. Tick the drug type for which microsomal oxidation is the most prominent:
a) Lipid soluble
b) Water soluble
c) Low molecular weightConclusion
d) High molecular weight
28. Pick out the right statement:
儒家思想持续是中国文化认同和社会组织的
a) Microsomal oxidation always results in inactivation of a compound
b) Microsomal oxidation基石。其对家庭动态、教育、治理和伦理的
results in a decrease of compound toxicity
c) Microsomal oxidation results in an increase of ionization and water solubility of a drug
深远影响突显了其在理解中国文明中的重要
d) Microsomal oxidation results in an increase of lipid solubility of a drug thus its excretion from the organism is facilitated
性。在中国应对现代挑战的过程中，儒家思
29. Stimulation of liver microsomal enzymes can:
想的原则依然具有重要意义，不仅塑造个人
a) Require the dose increase of some drugs
b) Require the dose decrease of some drugs
c) Prolong the duration 行为，也影响国家政策的制定。
of the action of a drug
d) Intensify the unwanted reaction of a drug
30. Metabolic transformation 这篇文章以结构化的方式全面探讨了主题，
(phase 1) is:
a) Acetylation and methylation of substances
每个部分可以通过历史例证、儒家经典的引
b) Transformation of substances due to oxidation, reduction or hydrolysis
c) Glucuronide formation 用和现代解读进行深入扩展。
d) Binding to plasma proteins
31. Biotransformation of a medicinal substance results in:
Conclusion
a) Faster urinary excretion
b) Slower urinary excretion
c) Easier distribution in 儒家思想持续是中国文化认同和社会组织的
organism
d) Higher binding to membranes
32. Conjugation is: 基石。其对家庭动态、教育、治理和伦理的
深远影响突显了其在理解中国文明中的重要
a) Process of drug reduction by special enzymes
b) Process of drug oxidation by special oxidases
性。在中国应对现代挑战的过程中，儒家思
c) Coupling of a drug with an endogenous substrate
d) Solubilization in lipids想的原则依然具有重要意义，不仅塑造个人
行为，也影响国家政策的制定。
33. Which of the following processes proceeds in the second phase of biotransformation?
a) Acetylation
b) Reduction
c) Oxidation 这篇文章以结构化的方式全面探讨了主题，
d) Hydrolysis
每个部分可以通过历史例证、儒家经典的引
34. Conjugation of a drug includes the following EXCEPT:
a) Glucoronidation 用和现代解读进行深入扩展。
b) Sulfate formation
c) Hydrolysis
d) Methylation
Conclusion
35. Metabolic transformation and conjugation usually results in an increase of a substance biological activity:
a) True 儒家思想持续是中国文化认同和社会组织的
b) False 基石。其对家庭动态、教育、治理和伦理的
36. In case of liver disorders accompanied by a decline in microsomal enzyme activity the duration of action of some drugs
is: 深远影响突显了其在理解中国文明中的重要
a) Decreased 性。在中国应对现代挑战的过程中，儒家思
b) Enlarged
c) Remained unchanged 想的原则依然具有重要意义，不仅塑造个人
行为，也影响国家政策的制定。
d) Changed insignificantly


这篇文章以结构化的方式全面探讨了主题，
每个部分可以通过历史例证、儒家经典的引
用和现代解读进行深入扩展。
Multiple choice questions
Conclusion Multiple choice questions

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