Week 5 Galen Practice Question Guide Answered Already Graded A+.

Aspirin - correct answer COX-2 inhibitor (enzyme that causes paion and inflammation) comes from salicylic acid decreases platelet aggregatopm Side Effects: dizziness, abdomnial pain Clopidogrel - correct answer Platelet Aggregation Inhibitor Used after MI/stroke to prevent a second even Can be used with aspirin Side effects: Bleeding, dizziness, epistaxis Heparin - correct answer Anticoagulant Used because of DVT, PE, or an evolving stroke Given Sub q, IV bolus, and IV infussion (not orally) Needs to be monitored Protamine Sulfate is the antidote LMWH is a safer, newer version Warfarin - correct answer Anticoagulant Used to prevent thromboembolic conditions (Thrombophlebitis, PE, and embolism) Vitamin K is the antidote Altepase - correct answer Thrombolytic Used for PE, DVT, non-coronary artial occlusion from an acute thromboembolism and thrombolic stroke Interacts with herbal products Procainamide - correct answer Antiarrhythmic Class 1: Sodium channel blockers antiarrythmic. Agranulocytosis, DILE, hypotension, QT. Beta Adrenergic Antagonist - correct answer Anti-dysrhythmics Class II - Used to manage abnormal heart rhythms and to protect the heart from a second attack Amiodarone (Cordarone) - correct answer Antidysrhythmic agent. Prolongs repolarization, relaxes smooth muscles, decreases vascular resistance. For ventricular fibrillation and unstable ventricular tachycardia. Incompatible with heparin, may be given in PO maintenance dose, monitor for respiratory complications. Verapamil (Calan) - correct answer Class IV Anti-dysrhythmics - Calcium channel blocker - Used to Tx angina, hypertension & arrhythmias Digoxin (Lanoxin) - correct answer cardiac glycoside Beta-block SE- nausea, vomiting, headache, rash, Inhibits Na-K pump in heart Beta Adrenergic Agonist Dopamine, epinephrine - correct answer Amrinone (Inocor) - correct answer Mechanism of action: Phosphodiesterase-3 inhibitor -> Increased cAMP -> increased PKA activity. Cardiac: results in increased L-type Ca2+ opening and increased cardiac output. Vascular: increased K+ channel opening results in vasodilation Use: ACUTE decompensated heart failure Side effects: arrhythmia Notes: IV for acute decompensa