Exam (elaborations)
USMLE Step 1 Pharm
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Exam of 28 pages for the course CTR exam quizzes with A+Answers 2024 at CTR exam quizzes with A+Answers 2024 (USMLE Step 1 Pharm)
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USMLE Step 1 Pharm-dronate - ANS-Bisphosphonate drug. Bone resorption inhibitor. Osteoporosis, Paget's,
Hypercalcemia
Acarbose - ANS-Alpha-glucosidase inhibitor. Blocks saccharide degradation and thus
glucose absorption by gut. Causes bloating.
Miglitol - ANS-Alpha-glucosidase inhibitor. Blocks saccharide degradation and thus
glucose absorption by gut. Causes bloating.
Mifepristone - ANS-Progesterone antagonist, Abortion, keep mi vagina pristine
Danazol - ANS-Androgen that blocks FSH, LH. Endometriosis.
Ergocalciferol - ANS-Vitamin D
Finasteride - ANS-5 alpha reductase inhibitor. Blocks DHT formation, baldness, BPH.
Fludrocortisone - ANS-Mineralocorticoid agonist. Adrenal insufficiency.
Glipizide - ANS-Sulfonylurea. Block ATP K channels to promote insulin release. Helps
insulin glide out of beta cells
Glimepiride - ANS-Sulfonylurea. Block ATP K channels to promote insulin release.
Helps insulin glide out of beta cells
Glyburide - ANS-Sulfonylurea. Block ATP K channels to promote insulin release. Helps
insulin glide out of beta cells
Aspart - ANS-Short-term insulin
Glulisine - ANS-Short-term insulin
Lispro - ANS-Short-term insulin
Insulin NPH - ANS-Medium length insulin.
Glargine - ANS-Long term insulin. Quite glarging around glucose, this insulin is
,determined!
Determir - ANS-Long term insulin. Quite glarging around glucose, this insulin is
determined!
Metformin - ANS-Decrease hepatic glucose output. Prevents formation of glucose
Methimazole - ANS-Thyroid hormone synthesis inhibitor.
Octreotide - ANS-Blocks GH, IGF-1, Serotonin, Gastroactive peptides Oxytocin -
ANS-Contracts uterus. Induce labor, stop uterine bleeding. Promote lactation.
Pegvisomant - ANS-GH antagonist. Acromegaly. Peg down your height!
Pioglitazone - ANS-Sensitizes muscle and adipose to insulin. Gets muscle and adipose
in the "zone" to accept insulin.
Risoglitazone - ANS-Sensitizes muscle and adipose to insulin. Gets muscle and
adipose in the "zone" to accept insulin.
Pramlintide - ANS-Amylin analog. Slows gastric emptying and makes you feel full. Less
glycemia after meals. Pram down all the food you want, your body wont absorb the
glucose.
Raloxifene - ANS-Bone resorption inhibitor. Estrogen agonist selective for bone. Relax
bone, you don't need to degrade, raloxifene is here.
Repaglinide - ANS-Stimulates insulin release. Also has the glide like sulfonylurea. Helps
insulin glide out of beta cells.
Nateglinide - ANS-Stimulates insulin release. Also has the glide like sulfonylurea. Helps
insulin glide out of beta cells.
Sitagliptin - ANS-DPP4 inhibitor, enhances incretin (GLP-1) action, which enhances
insulin secretion, muscle/fat uptake, decreases glucagon secretion.
Teriparatide - ANS-PTH, postmenopausal women. May cause osteosarcoma
-thromycin - ANS-Macrolide. 50S inhibitor.
, Aztreonam - ANS-Monobactam. Pseudomonas and enterobacteriae
Caspofungin - ANS-Antifungal that inhibits fungal cell wall synthesis
Cephalexin - ANS-1st gen cephalosporin
Ceftriaxone - ANS-3rd gen cephalosporin: pneumonia, gonorrhea, otitis media
Cefepime - ANS-4th gen cephalosporin. Citrobacter, enterobacter -floxacin -
ANS-Fluoroquinolones,topo2 inhibitor, tendionopathy/arthropathy Clindamycin
- ANS-50s inhibitor. Causes enterocolitis
Doxycycline - ANS-30S inhibitor. Teeth discoloration, photosensitivity. Intracellular bugs
Tetracycline - ANS-30S inhibitor. Teeth discoloration, photosensitivity. Intracellular bugs
Acyclovir - ANS-DNA polymerase inhibitor. Herpes zoster or simplex. Amphotericin B -
ANS-Binds ergosterol and forms K channel. Nephrotoxic. Clavulanate -
ANS-B-lactamase inhibitors
Tazobactam - ANS-B-lactamase inhibitors
Albendazole - ANS-Tubulin inhibitor, starves worms. Intestinal nematode infections.
Ethambutol - ANS-Mycobacteria drug that inhibits RNA synthesis. Can cause optic
neuritis. Causes things to appear Ethereal!
Foscarnet - ANS-Blocks viral DNA polymerase. CMV, resistant herpes. Renal failure
Fosfomycin - ANS-UTI's.
Gancyclovir - ANS-Blocks viral DNA polymerase. CMV. Decreases visual acuity, bone
marrow suppression
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