Is fat in the liver harmful? - ANS--Although fat in the liver is not a normal condition, it
can't cause damage by itself BUT it is a sign that other harmful conditions are
happening in the body.
Non-alcoholic steatohepatitis (NASH) - ANS-Liver inflammation due to fatty liver
Cirrhosis - ANS-scarring of the liver
hepatocellular carcinoma (HCC) - ANS-liver cancer
How can HCC develop? - ANS-HAFLD -> NASH -> cirrhosis -> HCC
Which disease is NAFLD almost as common as? - ANS-T2DM
What age group is seeing more NAFLD? - ANS-Adolescents
NAFLD is destined to become the leading cause of what? - ANS-Liver transplant
What is the leading cause of death in patients with NASH? - ANS-Cardiovascular
disease
How does NAFLD lead to hyperinsulinemia? - ANS-Causes decrease in insulin
clearance and increase in insulin resistance
How does NAFLD lead to T2DM - ANS-causes increase in glucose production
How does NAFLD lead to atherogenesis - ANS-causes increase in glucose production,
increase in cytokines, and increase in TG and ApoB
How does NAFLD lead to myocardinal dysfunction? - ANS-Causes decrease in ATP,
lipotoxicity, ischemia, and diastolic dysfunction which leads to heart disease
How does NAFLD lead to cardiovascular disease? - ANS-Causes hyperinsulinemia,
T2DM, atherogenesis, and myocardial
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Hkane. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.99. You're not tied to anything after your purchase.
