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Test Bank - Genetics and Genomics in Nursing and Health Care 2nd Edition (Beery ,2024)

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TEST BANK

Genetics and Genomics in Nursing and Health Care

BY: Theresa A. Beery, M. Linda Workman and Julia A. Eggert

2ND EDITION

, TABLE OF CONTENT

I. Basic Concepts from Molecular Genetics
Chapter 1. DNA Structure and Function
Chapter 2. Protein Synthesis
Chapter 3. Genetic Influences on Cell Division, Cell Differentiation, and Gametogenesis

II. Gene Expression
Chapter 4. Patterns of Inheritance
Chapter 5. Epigenetic Influences on Gene Expression (NEW)
Chapter 6. Autosomal Inheritance and Disorders (NEW)
Chapter 7. Sex Chromosome and Mitochondrial Inheritance and Disorders
Chapter 8. Family History and Pedigree Construction
Chapter 9. Congenital Anomalies, Basic Dysmorphology, and Genetic Assessment

III. Genomic Health Problems Across the Life Span
Chapter 10. Enzyme and Collagen Disorders
Chapter 11. Common Childhood-Onset Genetic Disorders
Chapter 12. Common Adult-Onset Genetic Disorders

IV. Genomic Influences on Selected Common Health Problems
Chapter 13. Cardiovascular Disorders
Chapter 14. The Genetics of Cancer
Chapter 15. Genetic Contributions to Psychiatric and Behavioral Disorders

V. Genomics and Disease Management
Chapter 16. Genetic and Genomic Testing
Chapter 17. Assessing Genomic Variation in Drug Response
Chapter 18. Health Professionals and Genomic Care

VI. Global Genomic Issues
Chapter 19. Financial, Ethical, Legal, and Social Considerations
Chapter 20. Genetic and Genomic Variation

,Genetics and Genomics in Nursing and Health Care Second Edition

Chapter 1: DNA Structure and Function

Multiple Choice
Identify the choice that best completes the statement or answers the question.

A. 1. In USED body or CELL area are most genes in humans located?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma membrane

A. 2. USED condition or statement exemplifies the concept of genomics rather than genetics?
A. The gene for insulin is located on chromosome 11 in all people.
B. Expression of any single gene is dependent on inheriting two alleles.
C. Sex-linked recessive disorders affect males more often than females.
D. One allele for each gene is inherited from the mother, and one is inherited from the
father.
A. 3. WHAT is the purpose of phosphorous in a DNA strand?
A. Linking the nucleotides into a strand
B. Holding complementary strands together
C. Ensuring that a purine is always paired with a pyrimidine
D. Preventing the separation of double-stranded DNA into single-stranded DNA

A. 4. WHAT is the term USED to define alternative forms of a gene that may result in different
expressionof the trait coded for by that gene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
D. 5. WHAT percentage of bases in a stretch of double-stranded DNA that contains 30% guanine
(G)bases would be adenine (A)?
A. 70%
B. 60%
C. 30%
D. 20%

C. 6. WHAT is the term USED to describe the organized picture of the paired chromosomes within
a CELL USED to determine whether chromosome numbers, structures, and banding patterns
arenormal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype

D. 7. WHAT would be the sequence of DNA that is complementary to a DNA section with the
basesequence of GGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC

,Genetics and Genomics in Nursing and Health Care Second Edition

B. 8. USED of these complementary base pairs form the strongest or “tightest” association?
A. Adenine and thymine
B. Cytosine and guanine
C. Guanine and thymine
D. Cytosine and adenine

A 9. WHAT activity occurs during M phase of the CELL cycle?
A. The CELL undergoes cytokinesis.
B. Activity stops, and the CELL “sleeps.”
C. All DNA is completely replicated.
D. The CELL greatly increases protein synthesis.

B. 10. USED chromosome number represents the euploid state for normal human somatic CELLs?
A. 44
B. 46
C. 47
D. 48

A. 11. How does the proteome differ from the genome?
A. The proteome changes in response to intraCELLular and extraCELLular signals.
B. The genome changes in response to intraCELLular and extraCELLular signals.
C. The proteome is stable in somatic CELLs and unstable in germ CELLs,
whereas the genome is stable in both somatic CELLs and germ CELLs.
D. The genome is stable in somatic CELLs and unstable in germ CELLs,
whereas the proteome is stable in both somatic CELLs and germ CELLs.
C. 12. WHAT is the most outstanding feature of a mature haploid CELL?
A. It is usually homozygous.
B. The sex chromosomes are missing.
C. Only one chromosome of each pair is present.
D. DNA synthesis occurs after mitosis instead of before.

D. 13. At WHAT phase of the CELL cycle are chromosomes visible as separate structures?
A. G1
B. G2
C. S
D. M

B. 14. USED statement about the CELL cycle phase of G0 is true?
A. Hyperplastic growth in place of hypertrophic growth
B. Performance of specific differentiated functions
C. Initiation and completion of nucleokinesis
D. Replication of DNA

B. 15. WHAT is the result of normal DNA replication?
A. Formation of two new daughter CELLs
B. Formation of two identical sets of DNA
C. Disappearance of the original parent CELL
D. Activation and attachment of spindle fibers

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