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ONS Chemotherapy Immunotherapy Certificate questions and answers.
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ONS Chemotherapy Immunotherapy Certificate questions and answers.
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ONS Chemotherapy ImmunotherapyCertificate
__________ has been described as a way to "fire up the immune system's response to
cancer" - correct answer-Immunotherapy
2 different ways that immunotherapies work against cancer: - correct answer-1. Triggering
the immune system to destroy cancer cells
2. Boost immune system's ability to fight cancer
2 main types of cancer vaccines - correct answer-Preventative/prophylactic
Treatment/therapeutic
2 types of aromatase inhibitors - correct answer-1. Steroidal (irreversible)
2. Nonsteroidal (reversible)
2 types of conditioning therapies: - correct answer-Myeloablative
Nonmyeloablative
2 types of therapies that commonly have cutaneous reactions: - correct answer-1. EGFR
inhibitor therapies
2. Antimetabolites
3 aromatase inhibitors - correct answer-Anastrozole
Letrozole
Exemestane
3 main goals of treatment: - correct answer-Cure
Control
Palliation
3 major phases of cell division: - correct answer-Interphase
Mitotic phase
Cytokinesis
3 steps of interphase: - correct answer-First growth phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
3 subcategories of alkylating agents: - correct answer-1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as
they work similarly)
3. Nitrosoureas
4 different types of medication dosing: - correct answer-1. Fixed doses
, 2. Weight-based doses
3. Body surface area (BSA) doses
4. Area under the curve (AUC) doses
4 phases of mitosis: - correct answer-Prophase
Metaphase
Anaphase
Telophase
6 main types of immunotherapy - correct answer-1. Monoclonal antibodies
2. Immune checkpoint inhibitors
3. Cancer vaccines
4. Nonspecific immunotherapies
5. Adoptive cell therapy (CAR T-cell therapy)
6. Oncolytic virus therapy
Active immunotherapy MOA - correct answer-Mount an immune response against tumor
*Should remember cancer cells long after treatment has stopped
Acute diarrhea lasts: - correct answer-1-2 days and resolves on its own
Adaptive immunity: - correct answer-Follows innate immunity if unsuccessful. Memory
immunity, including:
1. Humoral immunity (production of antibodies or immunoglobulins)
2. Cell mediated immunity (dependent upon T cells)
3. Regulatory T -cells (prevent autoimmune reactions and limit inflammatory responses)
Adoptive cell therapy MOA - correct answer-T cells collected from patient
T cells grown in laboratory
*This increases amount of T cells able to kill cancer cells or fight infections*
T cells given back to patient to help immune system
Adrenolytic agents MOA - correct answer-Suppress testicular and adrenal steroidogenesis,
rapidly reducing testosterone levels
Agents classified as irritants can cause: - correct answer-Inflammation
Pain
Burning
** Rarely cause tissue necrosis comparable to vesicants
Agents classified as vesicants can cause: - correct answer-Blistering
Significant pain
Tissue damage and destruction
**Lead to tissue death
An ANC of less that _____ is considered a risk for infection - correct answer-1,000
ANC calculation - correct answer-(% polys + % bands) x (WBC)/100
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