Exam (elaborations)
PA Psych Rotation EOR Meds
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PA Psych Rotation EOR Meds
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PA Psych Rotation EOR MedsSSRI mechanism of action - CORRECT ANSWER-Blocks the reuptake of
serotonin (only serotonin) thus increasing it's effects
SSRI medications - CORRECT ANSWER-Citalopram, Escitalopram Oxalate,
Fluoxetine HCL, Paroxetine HCL, Sertraline HCL, fluvoxamine
SSRI adverse effects - CORRECT ANSWER-Early: nausea, diaphoresis, tremor,
fatigue, drowsiness - should subside
Later: sexual dysfunction, weight gain, HA
GI bleeding, hyponatremia, serotonin syndrome, bruxism (teeth grinding tx with
cogentin), withdrawal syndrome (taper slowly), sleep disturbance (give in
morning), constipation
Paroxetine (paxil, paxil CR), Fluoxetine (Prozac, Sarafem), Sertraline (Zoloft),
Citalopram (Celexa) uses - CORRECT ANSWER-Depression, Panic disorder,
Generalized anxiety disorder, PMS, PTSD
Escitalopram (lexapro) uses - CORRECT ANSWER-Depression, Anxiety, Panic
disorder
Fluvoxamine (luvox, Luvox CR) uses - CORRECT
ANSWER-Obsessive-Compulsive disorder (OCD), Social Anxiety Disorder
SNRIs mechanism of action - CORRECT ANSWER-Block serotonin and
norepinephrine reuptake
SNRIs medications - CORRECT ANSWER-Venlafaxine (Effexor), Duloxetine
(Cymbalta), Desvenlafaxine (pristiq)
Venlafaxine common uses - CORRECT ANSWER-Anxiety and depression
Desvenlafaxine common uses - CORRECT ANSWER-Depression
, Duloxetine common uses - CORRECT ANSWER-Depression, anxiety,
neuropathic pain, stress incontinence, fibromyalgia
Venlafaxine adverse effects - CORRECT ANSWER-dry mouth, anxiety, insomnia,
headache, increased blood pressure, sexual dysfunction
Desvenlafaxine adverse effects - CORRECT ANSWER-Dry mouth, insomnia,
anxiety, nausea, constipation/diarrhea, sweating, dizziness
Duloxetine adverse effects - CORRECT ANSWER-Nausea, dry mouth,
constipation, fatigue, decreased appetite, somnolence and increased sweating
Milnacipran (savella) - CORRECT ANSWER-Like SNRI: Used for fibromyalgia
Milnacipram adverse effects - CORRECT ANSWER-Nausea, Insomnia, hot flush,
hyperhidrosis, palpitations, increased heart rate and increased blood pressure
Levomilnacipram (fetzima) - CORRECT ANSWER-Like SNRI: used for
depression
Bupropion (Wellbutrin) MOA - CORRECT ANSWER-Blockade of norepinephrine
and dopamine reuptake increases the available pool of these amines in the
synaptic cleft.
Bupropion (Wellbutrin) common use - CORRECT ANSWER-Depression,
smoking cessation, may improve sexual dysfunction of SSRI's
Bupropion adverse effects - CORRECT ANSWER-Agitation, anxiety, nausea,
vomiting, seizures, headaches, insomnia, rash
Bupropion contraindications - CORRECT ANSWER-active eating disorder,
seizure disorder, currently on an MAOI
Mirtazapine (Remeron) - CORRECT ANSWER-atypical antidepressant
Mirtazapine (Remeron) uses - CORRECT ANSWER-Depression, Anxiety,
Insomnia
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