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ONS ONCC Chemo Renewal Questions and answers
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ONS ONCC Chemo Renewal Questions and answers
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ONS ONCC Chemo Renewal50 - correct answer-The chance of developing colorectal cancer increases markedly after
age _____. Roughly 9 out of 10 people diagnosed with colorectal cancer are at least ____
years old.
65 - correct answer-The NCCN Older Adult Oncology Guidelines (version 1.2015) provides
information on what is included in a comprehensive geriatric assessment. Currently, more
than 60% of cancers in the United States occur in people age ______and older and as the
oncology world ages, nearly half (46%) of cancer survivors are 70 years of age or older
8.4% - correct answer-It is important that the nurse recognizes certain drugs that, when
given together, may result in a higher risk of adverse events. For example, in neoadjuvant
clinical trials using trastuzumab and pertuzumab, the incidence of decline in left ventricular
ejection fraction (LVEF) was 1.9% in patients treated with trastuzumab and docetaxel,
compared to ______ of those treated with trastuzumab, docetaxel, and pertuzumab
(Genentech, 2013).
85% - correct answer-Amgen (2007) defines RDI as "is a quantification of how closely an
administered course of chemotherapy treatment adheres to a specific regimen." Three
separate clinical trials evaluating outcomes in patients with breast cancer related to RDI
have demonstrated improved overall survival and 10-year disease free survival in patients
who receive a RDI > or = ____?_____
A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life
expectancy and risk of morbidity and mortality in the older patient. This assessment tool
would evaluate and include the following areas: functional status, socioeconomic issues,
psychosocial distress, comorbidities, cognitive function, nutritional status, polypharmacy, and
a medication review (NCCN Older Adult Oncology Guidelines, version 1.2015). - correct
answer-Due to Mrs. Turner's age and comorbidities, her oncologist performs a
comprehensive geriatric assessment. You know that this assessment covers all but which of
the following:
A dose-limiting toxicity of cyclophosphamide is hemorrhagic cystitis. Although it is more
commonly seen with high-dose therapy, it can still occur in patients receiving R-CHOP. -
correct answer-Which of the agents that Mr. Rylan is receiving in R-CHOP would be the
likely culprit if this is hemorrhagic cystitis?
a. Stop the paclitaxel infusion - correct answer-Mrs. Kearns is receiving her first dose of
paclitaxel and about 20 minutes into the infusion, you notice that she begins to start clearing
her throat a lot. She also states that she is having some lower back pain. You decide that
you will take another set of vital signs. While you are waiting for the monitor to reveal her
blood pressure, she begins to breathe heavier and appears short of breath.
What is the first/immediate thing you need to do for Mrs. Kearns?
, Administering HDs by any route (PO, IV, IT, etc.)
Handling any HD vials, ampules, or packaging materials
Introducing or withdrawing needles or dispensing pins from HD vials
Transferring drugs from HD vials to other containers using needles, dispensing pins, or
syringes
Opening ampules or HDs
Expelling air from an HD-filled syringe
Spiking IV bags containing HDs and changing IV tubing
Priming IV tubing with HDs
Handling HD leakage from tubing, syringe, and connection sites
Discontinuing infusions of HDs
Disposing of HDs and items contaminated by HDs
Handling the body fluids of a patient who had received HDs in the past 48 hours
Cleaning HD spills
Touching any surface that is potentially contaminated with HD residue - correct answer-PPE
should be worn whenever there is a potential that hazardous drugs could be released into
the environment like in the following situations:
Although all the other answers listed can happen with rituximab, you are most concerned
about the potential for a hypersensitivity reaction since this is rituximab and it is the patient's
first dose. - correct answer-What is the most important toxicity that you will monitor for with
rituximab especially since this is the patient's first dose of the agent?
Although hypersensitivity and infusion reactions can occur at any time and potentially with
any chemotherapy agent, there are certain agents that have a higher risk of causing a
reaction. For some agents, the reaction is more likely to occur after they have received a few
doses and have already been exposed to the same agent. On the other hand, there are
agents where the hypersensitivity reactions can occur almost immediately on exposure.
Reactions to platinum drugs (e.g., carboplatin, cisplatin, oxaliplatin) usually occur after
multiple treatments. However, reactions caused by taxanes (e.g., paclitaxel, docetaxel)
usually occur within the first hour of the first or second treatment. Reactions to monoclonal
antibodies like rituximab and cetuximab usually occur with the first treatment as well.
(Information from Zetka article) - correct answer-Which of the following agents would you
anticipate a hypersensitivity reaction more often occurring after the patient has already
received several doses?
Amsacrine
Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine - correct answer-DNA Nonbinding vessicants
ANC = (Neutrophils + Bands) x WBC / 100
To calculate the ANC:
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