a
1. Sustancia 1:
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
3 . No, porque a pesar de no tener grupos funcionales OH- o N+, su lipofilicidas es de 1.66, por lo
tanto, es lipofílico.
4. su lipofilicidad es de 1.66
5. Parche subdérmico,porque es una vía poco invasiva y es de carácter solido.
6. Transcutánea, porque cumple con las condiciones de fácil administración y no utiliza la vía oral.
7. El mecanismo de acción es por absorción subcutánea con receptores para antagonizar la acción
de las células parietales (CCK2)
8. pKa 9.2
Vd: 0.4 L
T ½ = 3h
e. que no seas toxico, que no sea teratogénico y que no genere neoplasias. Que sobreviva, que no
tenga efectos secundarios graves, que se pueda utilizar en varios prototipos con antecedentes
patológicos y de nutrición y que sea de efecto humano similar.
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