Class notes for BIOL 234 (Fundamentals of Genetics)
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Course
BIOL 234
Institution
University Of British Columbia (UBC
)
In-depth notes on various complex subjects in basic genetics with diagrams, pictures, graphs, and more to aid learning. Definitions are provided and various learning examples are present as well.
,LECTURE IA :
INTRO/REVIEW
>
- MELOSIS a core of the matter !
is
subject
cells
expressed in
GENES ~ (RNA) SPEC . PROTEIN
In fo
copied
↓
~
FUNCT . ORG .
PHENOTYPE
PROGENY (normal/wild)
↓
FUNCT . ORGO .
(pheno similar to
parents
KEY GENETIC PRINCIPLES A
D MUTAGENESIS Mutations DNA-loss of
change
: in or
function
gene
:
change in
p
neno .
> COMPLEMENTATION :
adding a normal
gene
to an
organism
normal
that
has a mutated one restore function and
can a
pheno.
SEGREGATION :
melosis determines how nuclear dis-
genes
> are
tributed from
parents to
progeny during sexual reproduction
LINKAGE : close
together chromosome often Inherited
genes
- on a
together
GENETIC GLOSSARY
Inheritance
-
-gene/allele
- dominance
- mutation
X
recombo/crossing -
over
-
transcription/translation
variation
phenotype
> in
- DNA & RNA
>
- chromosomes
- melosis
> mitosis
replication
>
-
-genetic mapping distance
phylogenetics
-
-genotype/phenotype
, LECTURE LB : REVIEW
>
- a GENOME of a cell is ALL the DNA in a cell
23
haploid gamete 22 autosomes
-
genes in ;
eukaryotic nuclear
genomes are
composed of linear chromosome
-
REPLICATED consist of "sister"
joined
> chromosomes 1 chromosomes
of the contromeric considered a SINGLE Chrome. until
region
anaphase (separation
D a GENOMPE is a combination of variation in DNA sequence for
I or more
genes and/or intergenic regions of an individual
* Internal &
external .
environ
affect expression
of
genotype
-
splicing poly-A,
tail 5',
capping
*
transcriptional
FUNCTION termination not
as
specific as
translation
termination
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