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MSP Test 1 Prep Actual Exam Questions 100% Correct Answers 2024 Version

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most versatile type of connective tissue - fibroblasts what can fibroblast differentiate into? - -bone -fat -smooth muscle -cartilage when do fibroblast become cartilage? - when in an enviornment without oxygen and cartilage is avascular when does cartilage become fibroblast - when oxygen ...

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  • July 7, 2024
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MSP Test 1 Prep | Actual Exam Questions |
100% Correct Answers | Verified
2024 Version
most versatile type of connective tissue - ✔✔fibroblasts



what can fibroblast differentiate into? - ✔✔

-bone

-fat

-smooth muscle

-cartilage



when do fibroblast become cartilage? - ✔✔when in an enviornment without oxygen and cartilage is
avascular



when does cartilage become fibroblast - ✔✔when oxygen is introduced to the cartilage is morphs back



what cells produce type I collagen? - ✔✔

bone

fat

smooth muscle



what cells produce type II collagen? - ✔✔cartilage



least specialized cell in body - ✔✔fibroblasts



-allows it to morph easily

,what embryonic derivative are fibroblast - ✔✔mesodermal derivative



what do fibroblasts secrete? - ✔✔extracellular matrix



-collagen

-prosteoglycans

-elastin

-fibronectin and other structural proteins



what is collagen - ✔✔-present in almost all organs

-holds cells together

-gives tissue structural integrity



mammalian protein - ✔✔25% of all mammalian protein is collagen



signs and symptoms a patient with collagen synthesis disorder may present with - ✔✔-excessive
bleeding

-hypermobility

-joint laxity

-bone fragility

-slower healing time



sign vs. symptom - ✔✔sign- what doctor observes



symptom- what patient complains of



collagen synthesis stages - ✔✔1. intracellular stage

2. extracellular stage

, intracellular stage of collagen synthesis - ✔✔from amino acid synthesis to procollagen



extracellular stage of collagen synthesis - ✔✔from procollagen to mature collagen



what occurs in the rough ER - ✔✔mRNA transcription and translation



amino acid arrangement - ✔✔arranged into alpha-chains



sequence of amino acids - ✔✔genetically predetermined



critical in determining the collagen end product



amino acid chain composition - ✔✔repeating Gly - X - Y



-X and Y can be any other animo acid, but gylcine appears every 3rd



most common AA foun on X position of chain - ✔✔proline



common AA found in Y position of chain - ✔✔Hydroxyproline and Hydroxylysine



what do Imino acids do - ✔✔creates rigid cyclic structure that will limit the rotation of the chain



what two amino acids are Imino acids - ✔✔proline and hydroxyproline



smallest amino acid - ✔✔glycine



what gives the chain a helical structure - ✔✔glycine

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