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NR566 Final (Advanced Pharmacology for Care of the Family) Rated A+ $10.59   Add to cart

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NR566 Final (Advanced Pharmacology for Care of the Family) Rated A+

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NR566 Final (Advanced Pharmacology for Care of the Family) Rated A+ ### Anti-Androgens - Medications: - Finasteride (Propecia) - Leuprolide (Eligard, Lupron, Lupron Depot) - Spironolactone (Aldactone) ### Finasteride (Propecia, Proscar) - Mechanism: Inhibits the conversion of testosterone to di...

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  • July 7, 2024
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NR566 Final (Advanced Pharmacology for Care of the Family) Rated A+
### Anti-Androgens


- Medications:


- Finasteride (Propecia)


- Leuprolide (Eligard, Lupron, Lupron Depot)


- Spironolactone (Aldactone)




### Finasteride (Propecia, Proscar)


- Mechanism: Inhibits the conversion of testosterone to dihydrotestosterone.


- Uses:


- Benign Prostatic Hyperplasia (BPH)


- Male pattern baldness


- Therapy Duration: Requires 3 months to see benefits; effects reverse within 12 months after stopping

the medication.


- Side Effects:


- Decreased libido


- Impotence




### Dutasteride (Avodart)

,- Mechanism: 5-alpha reductase inhibitor.


- Uses: Treats BPH.


- Additional Information:


- Can remain in the serum for up to 6 months after discontinuation.


- Absorbed through the skin; pregnant women should avoid handling capsules due to the risk of fetal

anomalies in male fetuses.


- Side Effects:


- Decreased libido


- Impotence




### Leuprolide Acetate (Lupron)


- Mechanism: Luteinizing hormone-releasing hormone agonist.


- Effects: Creates a reversible state similar to orchiectomy or oophorectomy.


- Uses: Treats advanced prostate cancer.- Management of endometriosis


- Uterine fibroids


- polycystic ovarian disease


- central precocious puberty in peds




Flutamide (Eulexin, Euflex) ✅Truly non-steroidal agent

, Used to tx:


-Advanced prostate cancer


-female androgen excess syndrome




Adverse Effects in males


- gynecomastia


-reversible liver toxicity




Black Box Warning


-hepatic failure


-hepatic encephalopathy


Basline/monthly liver function test for 1st 4 months




Spironolactone (Aldactone) ✅aldosterone antagonist


potassium sparing diuretic




used for tx:


-female hirsutism (abnormal growth of hair)


-acne

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