Exam (elaborations)
PSCI 501 FINAL EXAM Questions With Well Elaboration Answers.
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Sotorasib - correct answer • Introduction to disease state: KRAS G12C mutant non-small cell lung cancer • Mechanism of action: Binds to the cysteine residue in KRAS g12C mutation and holds the protein in its inactive form (KRAS inhibitor) • Hit discovery: (must bind to cystei...
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