Write a short essay explaining the homeostatic functioning of the nephron if a
person is suffering from dehydration
• When the water content of the body drops below normal
• the osmotic potential of the blood increases √
• which stimulates the osmoreceptors in the hypothalamus √
• which produces ADH
• to transmit impulses to the pituitary gland (hypophysis) √
• to release more ADH √ in to the blood
• ADH is transported by bloodstream to the kidney √
• where this hormone increases the permeability √ of the walls of the
• distal convoluted tubule and collecting duct √
• more water √ is re-absorbed from the filtrate √
• and small amount of concentrated urine √ is excreted
• the adrenal gland √ secrete aldosterone √
• which cause sodium ions √ to be actively √ pumped out of the filtrate √
• in the ascending limb of loop of Henle √
• in to the tissue fluid of the kidney medulla √
• this creates a low water potential √ and
• water moves by passive osmosis √
• from the collecting tubule √
• in to the tissue fluid of the medulla √
• from where it is absorbed in to the blood capillaries √
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