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Summary - Histology of lymphoid organs

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The histology of lymphoid organs is summarized with important key points that are important. Detailed explanation of the lymphoid organs.

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  • July 11, 2024
  • 6
  • 2023/2024
  • Summary
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Histology

, ~
Histology of Lymphoid Organs
Lymphoid Organs:
Lymphoid
·
system is responsible for the immunological defense of the body Lymphoid organs
. are
designed to
gather
& destroy infectious microorganisms & to store lymphocytes .




· Two
categories :




"Primary central Lymphoid organs : responsible for the development of lymphocytes into mature immunocompetent cells
.



~
Fetal liver, prenatal & postnatal bone marrow , a thymus

2 Secondary (peripheral) Lymphoid organs : Responsible for the proper environment in which immunocompetent cells can react with


eachother ,
along with
antigens &other cells to mount an
immunological challenge agains invading antigens or
pathogens .




~

Lymph nodes , spleen, I mucosa associated Lymphoid tissue .




Thymus:
A lymphoid organ located in the mediastemum It is mostly active
central .


during youth.
It is the site of maturation of T dymphocytes & secretes thymic hormones such as thymosin thymopoietin thymulin a
, , ,




thymic humoral factor .




* It differs from other lymphoid organs since it functions strictly in lymphocyte maturation . It also consists of thethymic epithelial cells .




* Cortex of thymus :

Contains
developing
~

thymocytes (T Lymphocytes) Macrophages
, &,
~

Thymic cortical epithelial cells . These cells are linked to eachother by
desmosomes that surround the capillary.
A dual basal
Lamina is present in the space between epithelial cells & capillaries.

~
The thymic endothelial cells , basal Lamina, & endothelial cells form the

functional blood thymus -
barrier. It prevents the contact of
antigenic material
with the
developing
Flymphocytes .

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