Pathophysiology - SCI225-06
1. The nurse is caring for a pa- Cystic Fibrosis
tient with a genetic disease
that is transmitted through
autosomal recessive inher-
itance. Which is the most
likely diagnosis for the pa-
tient?
2. Adaptive cellular mecha- protect cells from injury
nisms function to:
3. If a patient has liquefac- brain
tive necrosis, which organ
should the nurse assess
first?
4. The nurse in the genetics Huntington disease
clinic is describing a genet-
ic disease that leads to pro-
gressive dementia in mid-
dle to later adulthood. To
which disease is the nurse
most likely referring?
5. The triplet of base pairs Codon
necessary to code for a
specific amino acid is
called a:
6. The outward manifestation phenotype
of a disease, often influ-
enced by both genes and
the environment, is called
the disease:
7. The condition that occurs a "monosomy"
when a zygote is missing in
each cell is referred to as:
8. transcription
, Pathophysiology - SCI225-06
The process by which RNA
is formed from DNA for pro-
tein synthesis as:
9. The somatic cell that con- an euploid cell
tains a multiple of 23 chro-
mosomes is called:
10. Which is the chief function protein synthesis
of ribosomes?
11. A disease results in the ac- Tay-Sachs disease
cumulation of lipids in the
nerve cells of the brain:
12. Cellular atrophy is: a decrease in cell size
13. The process by which cells Apoptosis
program themselves to die:
14. Which causes metaplasia Cell injury from noxious stimuli
in humans?
15. The postmortem decrease algor mortis
in a patient's body temper-
ature will be documented
as:
16. Dysplasia is characterized cell secretions
by abnormal changes in:
17. Clastogens are agents that chromosomal breakage
cause:
18. Which organ is most fre- liver
quently affected by chronic
alcohol (ethanol) injury?
19. The nurse documents "tat- gunshot wounds
tooing and stippling" in a
, Pathophysiology - SCI225-06
trauma patient. Which type
of injury does this patient
have?
20. When a patient has an an avulsion
extreme laceration (lacer-
ation with a flap), which
medical term should the
nurse document on the
chart?
21. A patient with a combined T & B lymphocytes
immune deficiency lacks:
22. When assessing a patient arthralgia, anemia, and rash
with SLE (Systemic lu-
pus erythematosus), you
should expect to identify:
23. Your patient is having a re- Type 1
action to a bee sting. Which
type of hypersensitivity are
they displaying?
24. The major phagocytic cells Neutrophils and macrophages
in inflammation are:
25. what is the role of plas- controls clotting by breaking down fibrin
min in the inflammatory re-
sponse cycle?
26. among the many innate de- skin and mucous membranes
fenses the body has to
pathogens, the first line of
defense is the:
27. which substance is re- interferon
leased during a viral infec-
tion and signals neighbor-
, Pathophysiology - SCI225-06
ing cells to enhance viral
defenses?
28. what term is used to de- engulfment
scribe the process of endo-
cytosis?
29. DiGeorge syndrome is Thymus
characterized by absence
or underdevelopment of
which organ?
30. You are planning a commu- Women, 20-40 years old.
nity teaching event about
systemic lupus erythe-
matosus (SLE). To which
population should your
teaching be primarily tar-
geted?
31. A 5-year-old male presents D. Intracellular dehydration
to the ER with delirium and
sunken eyes. After diag- Rationale: A hypertonic solution would cause
nosing him with severe de- fluid to move into the extracellular space, lead-
hydration, the primary care ing to intracellular dehydration. With this so-
provider orders fluid re- lution, his symptoms will not subside quickly
placement. The nurse ad- because his cells will lose fluid. His intracellu-
ministers a hypertonic in- lar volume will decrease and his extracellular
travenous solution. Which volume will increase.
of the following would be
expected?
A. Symptoms subside
B. Increased ICF volume
C. Decreased ICF volume
D. Intracellular dehydration
32. A 35-year-old male weighs D. 42 L
70 kg. Approximately how
much of this weight is con- Rationale: The total volume of body water for a
1. The nurse is caring for a pa- Cystic Fibrosis
tient with a genetic disease
that is transmitted through
autosomal recessive inher-
itance. Which is the most
likely diagnosis for the pa-
tient?
2. Adaptive cellular mecha- protect cells from injury
nisms function to:
3. If a patient has liquefac- brain
tive necrosis, which organ
should the nurse assess
first?
4. The nurse in the genetics Huntington disease
clinic is describing a genet-
ic disease that leads to pro-
gressive dementia in mid-
dle to later adulthood. To
which disease is the nurse
most likely referring?
5. The triplet of base pairs Codon
necessary to code for a
specific amino acid is
called a:
6. The outward manifestation phenotype
of a disease, often influ-
enced by both genes and
the environment, is called
the disease:
7. The condition that occurs a "monosomy"
when a zygote is missing in
each cell is referred to as:
8. transcription
, Pathophysiology - SCI225-06
The process by which RNA
is formed from DNA for pro-
tein synthesis as:
9. The somatic cell that con- an euploid cell
tains a multiple of 23 chro-
mosomes is called:
10. Which is the chief function protein synthesis
of ribosomes?
11. A disease results in the ac- Tay-Sachs disease
cumulation of lipids in the
nerve cells of the brain:
12. Cellular atrophy is: a decrease in cell size
13. The process by which cells Apoptosis
program themselves to die:
14. Which causes metaplasia Cell injury from noxious stimuli
in humans?
15. The postmortem decrease algor mortis
in a patient's body temper-
ature will be documented
as:
16. Dysplasia is characterized cell secretions
by abnormal changes in:
17. Clastogens are agents that chromosomal breakage
cause:
18. Which organ is most fre- liver
quently affected by chronic
alcohol (ethanol) injury?
19. The nurse documents "tat- gunshot wounds
tooing and stippling" in a
, Pathophysiology - SCI225-06
trauma patient. Which type
of injury does this patient
have?
20. When a patient has an an avulsion
extreme laceration (lacer-
ation with a flap), which
medical term should the
nurse document on the
chart?
21. A patient with a combined T & B lymphocytes
immune deficiency lacks:
22. When assessing a patient arthralgia, anemia, and rash
with SLE (Systemic lu-
pus erythematosus), you
should expect to identify:
23. Your patient is having a re- Type 1
action to a bee sting. Which
type of hypersensitivity are
they displaying?
24. The major phagocytic cells Neutrophils and macrophages
in inflammation are:
25. what is the role of plas- controls clotting by breaking down fibrin
min in the inflammatory re-
sponse cycle?
26. among the many innate de- skin and mucous membranes
fenses the body has to
pathogens, the first line of
defense is the:
27. which substance is re- interferon
leased during a viral infec-
tion and signals neighbor-
, Pathophysiology - SCI225-06
ing cells to enhance viral
defenses?
28. what term is used to de- engulfment
scribe the process of endo-
cytosis?
29. DiGeorge syndrome is Thymus
characterized by absence
or underdevelopment of
which organ?
30. You are planning a commu- Women, 20-40 years old.
nity teaching event about
systemic lupus erythe-
matosus (SLE). To which
population should your
teaching be primarily tar-
geted?
31. A 5-year-old male presents D. Intracellular dehydration
to the ER with delirium and
sunken eyes. After diag- Rationale: A hypertonic solution would cause
nosing him with severe de- fluid to move into the extracellular space, lead-
hydration, the primary care ing to intracellular dehydration. With this so-
provider orders fluid re- lution, his symptoms will not subside quickly
placement. The nurse ad- because his cells will lose fluid. His intracellu-
ministers a hypertonic in- lar volume will decrease and his extracellular
travenous solution. Which volume will increase.
of the following would be
expected?
A. Symptoms subside
B. Increased ICF volume
C. Decreased ICF volume
D. Intracellular dehydration
32. A 35-year-old male weighs D. 42 L
70 kg. Approximately how
much of this weight is con- Rationale: The total volume of body water for a
