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Pathophysiology lecture 6 drexel (1)
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Pathophysiology lecture 6 drexel (1)
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Pathophysiology lecture 6 drexeldisorders of arterial circulation - ANS--hyperlipidemia
-atherosclerosis
-vasculitides
-extremities
-aneurysms
what does arterial system do? - ANS-deliver nutrients and oxygen to tissues
where does arterial go? - ANS-away from heart. venial beings it back to lungs
disorders of arterial system leads to what? - ANS-ischemia which leads to hypoxia, thrombus
formation associated with platelet adherence, and weakening of walls
atheroschlerosis - ANS-progressive disease with fibrofatty plaques in intima of large and
medium vessels that decrease blood supply
aneurysms - ANS-dilation of artery due to weakening of vessel wall, as it becomes larger there
is more pressure and may rupture. Rupture is the part that is bad. Hard to diagnose because
blood will still pass until rupture.
LDL and HDL - ANS-LDL-protein 25% HDL-50%
processing LDL - ANS-goes into receptors on liver, some is converted to HDL, bile acid and
cholestrelol come out of liver
good number for cholesterol - ANS-under 100, 60 and over for HDL, 40 and under for LDL
what leads to hypercholesterolemia - ANS-1. genetics
2. obesity
3. diabetes mellitus
genetics and hypercholesterolemia - ANS-lack of LDL receptors on the liver, can't get into liver
to be broken down so sky rockets
obesity and hypercholesterolemia - ANS-too many calories and LDL can shut down receptors
and reduce them
diabetes and hypercholesterolemia - ANS-predisposed to too many triglycerides, low HDL high
LDL
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