Exam (elaborations)
NUR 2060 Cancer Drugs (3)
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NUR 2060 Cancer Drugs (3)
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NUR 2060 Cancer DrugsWhat is allopurinol (Zyloprim) used to treat? - ANS---its an anti-uric drug that you start BEFORE
chemo to prevent tumor lysis syndrome (TLS)
What kind of drug is aprepitant (Emend)? What other drug(s) should this drug be given with? -
ANS---neurokinin antagonists--given with dexamethasone & serotonin antagonist
What is cyclophosphamide (Cytoxan) used to treat? Action? ADRs? Toxicity? - ANS---cytotoxic
agent
--action is to alter DNA
--toxicity causes bone marrow suppression (most serious) and acute hemorrhagic cystitis
(unlikely)
--ADRs: N/V, alopecia
What is cisplatin (Platinol) used to treat? ADRs? - ANS---used in combination to treat: ovarian &
cervical CA, testicular CA, lung CA, colon CA
--ADRs: myleosuppression, N/V, neuropathy, hypersensitivity, renal toxic
What is carmustine (BCNU) used to treat? What else (other than cancer) can the drug be used
to treat/help? - ANS---used to treat: primary & metastatic CA's of CNS, Hodgkin &
non-Hodgkin's myeloma, liver, colon, rectum and stomach CA
--used in high dose regimes for transplants
What is methotrexate (Rheumatrex) used to treat? ADRs? - ANS---folic acid antagonist--used in
solid and liquid tumors
--ADRs: myelosuppression, GI toxicity
What is fluorouracil (5FU) used to treat? ADRs? - ANS---for tx of: solid tumors in breast, colon,
rectum, stomach and pancreas
--continuous infusion
--ADRs: GI toxicity, myelosuppression, hand-foot syndrome
What is bleomycin (Blenoxane) used for? ADRs? - ANS---anti-tumor antibiotic
--for tx of: lymphoma, squamous cell carcinoma, testicular cancer--ADRs: pulmonary fibrosis,
pneumonitis, anaphylaxis
What is doxorubicin (Adriamycin) used for? ADRs? - ANS---anti-tumor antibiotic
--in both solid and liquid tumors--ADRs: myelosuppression, mucositis, tissue necrosis, cardiac
damage--solution is RED so urine with me red for 24hr
What is vincristine (Oncovin) used to treat? Action? - ANS---prevents cell division in "M" phase
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