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Nurs 615 Pharm Exam 1 - Maryville.

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Nurs 615 Pharm Exam 1 - Maryville.

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  • July 22, 2024
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Nurs 615 Pharm Exam 1 - Maryville
According to the WHO what is the first step in the prescribing process? - The first step is

to define the patient's problem



Acids give ___ to bases - Hydrogen



Activation of Alpha 2 receptors results in - Decreases of HR and BP



adrenergic agonsists are made of 2 groups called... - catacholemine, non catacholemine



adverse drug reactions associated with use of beta-blockers include (22) - nausea,

diarrhea, bronchospasm, dyspnea, cold extremities, exacerbation of Raynaud's,

syndrome, bradycardia, hypotension, heart failure, heart block, fatigue, dizziness,

alopecia, abnormal vision, hallucinations, insomnia, nightmares, sexual dysfunction,

erectile dysfunction, and or alteration of glucose and lipid metabolism



Adverse effects associated with beta-2 adrenergic receptor antagonists' activity will

include - bronchospasm, peripheral vasoconstriction, alteration of glucose and lipid

metabolism, specifically hyperlipidemia, impaired insulin release. These are less common

with the beta 1 selective or cardio selective agents but receptor selectivity diminishes at

higher doses.



All cholinergic blockers are used to treat - spastic or hyperactive conditions of the GI and

urinary tracts because they relax muscles and decrease GI secretions. These drugs may

be used to relax the bladder and to treat urinary incontinence. The quaternary ammonium

,and amine compounds such as propantheline are the drugs of choice for these conditions

because they cause fewer adverse reactions than belladonna alkaloids. •



Alpha 1 leads to inhibition of renin release which effects BP by - Renin is excreted by the

kidneys and helps to lower BP



Alpha 1 leads to... - vasoconstriction, dialation of pupil, contraction, urinary retention,

glycogenolysis, inhibition or renin release



ALpha 1 receptors are located mainly on... - Vascular smooth muscle (blood vessels,

arteries, veins, urinary sphincters,)



Alpha 2 receptors affect the pancreas by - inhibiting insulin production



Alpha 2 recpetors are generally considered to work with the..... - GI system



Alpha blockers end in "zosin" are mostly used for - BPH and sometimes HTN. Adverse

effects of orthostatic hypotension. They block the effects of catecholamines at the alpha 1

receptors in vascular smooth muscle and also smooth muscle of the bladder neck and

prostate



An example of type 2 hypersensitivity is the - ABO blood incompatibility where the red

blood cells have different antigens causing them to be recognized different. B-cell

proliferation will take place in antibodies until foreign blood types are produced. IgG and

IgM antibodies bind to these antigens to form complexes that activate the classical

, pathway of the complement activation to eliminate cells presenting foreign antigens. that is

mediators of acute inflammation are generated at the site and the membrane attack of

complexes cause cell lysis and death. This reaction takes between hours to a day.



Another place to find Beta 1 receptors is on the X, which releases X - Kidney, renin; which

increases BP



Anticholinergic Drugs - The anticholinergics and antispasmodics are a group of medicines

that include the natural belladonna alkaloids (atropine, belladonna, hyoscyamine, and

scopolamine) and related products.



Anticholinergic drugs are used to treat a variety of conditions, such as - GI disorders like

gastritis, diarrhea, pylorospasm, diverticulitis, ulcerative colitis, nausea and vomiting;

genitourinary disorders cystitis, urethritis, prostatitis; respiratory disorders like asthma,

chronic bronchitis, COPD, sinus bradycardia due to hypersensitive vagus nerve, insomnia

although usually only for a short term basis, dizziness including vertigo, motion sickness

related symptoms.



Anticholinergics are divided into three categories in accordance with their specific target in

the central and - or peripheral nervous system, this includes/ antimuscarinic agents,

ganglionic blockers, and neuromuscular blockers.



Anticholinergics produce muscarinic blockade against acetylcholine. Muscarinic receptors

are all over the body. The goal of administration is to compete with - acetylcholine at those

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