NUR 325 Exam 3 Drugs Questions and Correct Answers ARBs Answer - Losartan Losartan mechanism of action Answer - blocks angiotensin II receptors and blocks aldosterone Losartan therapeutic effect Answer - Treats hypertension, heart failure and myocardial infarction Losartan adverse effects Answer - Fatigue, headache, dizziness, rare angioedema Losartan interac tions Answer - NSAIDs and diuretics ARBs benefit over ACEI Answer - no cough, no hyperkalemia, no first dose hypertension ACE Inhibitors Answer - Captopril Captopril mechanism of action Answer - Reduces conversion of angiotensin I to II, inhibits vasoconstriction, inhibits aldosterone Captopril therapeutic effect Answer - Treats hypertension, heart failure, myocardial infarction Captopril adverse effects Answer - hypotension after first dose , hyperkalemia, cough, angioedema, metallic taste in mouth Captopril interactions Answer - NSAIDs, diuretics Aldosterone Antagonist Answer - Eplerenone Eplerenone mechanism of action Answer - Blocks aldosterone receptors Eplerenone therapeutic ef fect Answer - Treats hypertension and heart failure Eplerenone adverse effects Answer - Diarrhea, abdominal pain, cough, fatigue, hyperkalemia
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