NUR210 / NUR 210 Exam (Latest ):
Principles of Pharmacology | Questions and Verified
Answers | 100% Correct | Grade A - Galen
Pharmacokinetics is:
A. The effect the drug has on the body.
B. The adverse response of the drug on the body.
C. The effect the body has on the drug.
D. The clinical formulation of the drug - ANSWER C. The effect the body has on the drug.
Absorption, distribution, metabolism, excretion
The ratio of minimum effective concentration (MEC) to minimum toxic concentration (MTC) of a drug is the: - ANSWER therapeutic window
half life: - ANSWER the time it takes for the plasma concentration of the drug to be reduced to half of its original value Drug clearance formula - ANSWER rate of drug elimination / plasma concentration of the drug
steady state - ANSWER when the rate of drug input equals the rate of drug elimination
Which of the following actions triggers a rise in membrane or action potential of a cell?
A. Opening of the voltage gated sodium ions
B. Closure of voltage gated sodium ions
C. Opening of calcium ion channel
D. Opening of potassium voltage gated channels - ANSWER A. Opening of the voltage gated sodium ions
Before stimulation, a cell has a slightly negative electric charge (compared with ECF). Outside is more positively charged. When stimulus is encountered, sodium ion channel opens and sodium rushes into the cell, causing depolarization (rise in membrane/action potential)
The process by which a drug's activity is altered in order to prepare it for excretion: - ANSWER biotransformation The amino acid found in dairy products, fish, and eggs is tyrosine. The amino acid from which tyrosine is made is: - ANSWER phenylalanine.
People take tyrosine to help manage depression, ADD, ADHD, narcolepsy, and to improve alertness following sleep deprivation
The correct order of the transmission of a neurotransmitter is presynaptic preparation followed by: - ANSWER arrival of action potential, release of transmitter, receptor interaction, and the termination of transmitter action
In the pharmacokinetics of a drug, the rate of metabolism: - ANSWER varies widely between patients, influenced by genetic and environment factors-->major reason for differences in plasma concentration of some drugs after a standard dose, leading to a wide variation in drug response
Metabolism: - ANSWER process by which drugs are chemically changes from a lipid-soluble form suitable for absorption and distribution to a more water-soluble form that is
suitable for excretion
The protein-bound part of a drug is: - ANSWER Inactive and acts as a reservoir
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