BRM's
(Biological
Response
Modifiers)
used
for
RA
Abatacept
-
ANS-Monitor
for
dyspnea,
wheezing,
Flushing,
and
itching
Abatacept
-
ANS-Patient
is
to
report
cough,
dizziness
and
sore
throat;
not
to
receive
love
vaccines
while
taking
this
drug
Anakinra
-
ANS-May
cause
severe
decrease
in
WBC
count
Anakinra
-
ANS-Patient
is
to
report
respiratory
symptoms
such
as
cough
and
fever;
malignancies
can
result
Crowds
Live
vaccines
Ppl
with
infections
-
ANS-What
patients
should
avoid
when
taking
BRMs?
Etanercept
(Enbrel)
Infliximab
Adalimunab
Anakinra
-
ANS-After
administration,
monitor
site
for
reaction
Golimumab
-
ANS-Adverse
effects
include
HTN,
GI
distress
and
infection
Golimumab
-
ANS-Patient
is
to
report
s/s
of
infection,
including
fever
and
malaise;
should
avoid
live
vaccines
while
taking
this
drug
Infliximab
-
ANS-Only
BRM
that
shouldn't
be
refrigerated
Infliximab
-
ANS-Patient
is
to
report
chest
pain
or
difficulty
breathing
during
infusion,
and
monitor
bp
Rituximab
-
ANS-Drug
has
a
BLACK
BOX
WARNING
about
serious
infections
Rituximab
-
ANS-Observe
for
infusion
reaction
as
for
entanercept
serious
infection
TB
MS
-
ANS-Contraindicated
in
which
patients?
Tocilizumab
-
ANS-May
cause
decrease
in
WBCs,
platelets
and
liver
dysfunction
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