NSG 210 Exam #3-Questions with Correct Answers/
Verified/ Latest Update
Chlordiazepoxide - ✔✔BZD, binds to BZD receptors and enhances GABA
Clonzaepan - ✔✔Klonopin, BZD, binds to BZD receptors and enhances GABA
Diazepam - ✔✔Valium, GABA receptor agonist, BZD
Midazolam - ✔✔GABA agonist, pre-op anesthetic and muscle , BZD
Lorazepan - ✔✔Ativan, Binds to BZD receptors, enhances GABA. Used for anxiety and status
epilepticus. BZD
Oxazepam - ✔✔Anxiety and alcohol withdrawl, BZD
Temazepam - ✔✔Restoril, used for INSOMNIA, BZD
Estazolam - ✔✔BZD antianxiety
Flurazepam - ✔✔Binds to BZD receptors (BZD), enhances GABA effects, used for insomnia
Triazolam - ✔✔Binds to BZD receptors (BZD), enhances GABA effects DON'T USE THIS DRUG
Flumazenil - ✔✔BZD ANTAGONIST and GABA ANTAGONIST. Only one approved use: after
surgery, if someone has respiratiory depression from anesthesia and BZD are prolonging
recovery
Buspirone - ✔✔Buspar, 5-HT1 agonist, used for generalized anxiety disorder, no abuse, 10%
get more anxious
,Zolpidem - ✔✔Ambien. SELECTIVE BZD (1) no rebound insomnia
Zaleplon - ✔✔Sonata, SELECTIVE BZD (1) no rebound insomnia, induces sleep in pts with
mid-cycle awakening problems
Eszopiclone - ✔✔Lunesta, no rebound insomnia, Non-BZD (selective)
Ramelteon - ✔✔MELATONIN binder, does NOT bind GABA, Non-BZD used for insomnia.
CONTRAINDICATION: Fluvoxamine
Alprazolam - ✔✔Xanax, high abuse, Non-BZD sedative hypnotic
Melatonin - ✔✔induces sleep, resets body clock, can cause suicidal ideation, tolerance very
quickly
Pentobarbitol - ✔✔Class II drug, GABA binder, sedative, causes resp depression and severe
dependence/withdrawl. BARBITURATE
Secobarbitol - ✔✔Class II drug, GABA binder, sedative, causes resp depression and severe
dependence/withdrawl, BARBITURATE
Phenobarbitol - ✔✔Class IV, GABA binder, last choice for seizure control, longer acting.
BARBITURATE
Disulfram - ✔✔Antabuse, alcohol hydrolysed from alcohol to aldehyde, but CANNOT turn
into acetate and will make the pt feel sick.
Naltrexone - ✔✔Trexan, blocks opoid receptors, helps with drink/drug cravings
Methylphenidate - ✔✔Ritalin, used for ADHD and narcolepsy
,Amphetamine - ✔✔REVERSES the transporter of DA and NE, forcing it out rather than back
in.
d-Amphetamines - ✔✔Adderall for ADHD and also for narcolepsy
Lys-dexamethamphetamine - ✔✔Vyvanse, clever drug for ADHD that reduces efficacy when
injected to prevent abuse.
Pemoline - ✔✔Cylert, no abuse, doesn't work quite as well, can cause liver toxicity, used for
ADHD. Reduced reuptake of NE and DA.
Atomoxetine - ✔✔NE selective for ADHD. VERY anticholinergic so bad for BPH.
Modafinil - ✔✔Provigil. Amphetamine-like, less abuse, first choice for narcolepsy. Probably
blocks reuptake of DA and NE.
Cocaine - ✔✔Blocks reuptake of NE, 5-HT and MOST IMPORTANTLY DA!!! Local anesthetic.
Morphine - ✔✔...
Methadone - ✔✔Mu agonist, 24-48 hr half life, used in tx of heroin addicts
Meperidene - ✔✔mu receptor used in childbirth (increases GABA)
Fentanyl - ✔✔Mu agonist as a patch for pain relief
Sufentanil - ✔✔Very powerful mu receptor agonist, elephant tranquilizer
Oxycodone - ✔✔Mu agonist, intermediate abuse potential, good for dull achy pain
, Codeine - ✔✔CYP2D6
Hydrooxycodone - ✔✔Mu agonist, intermediate abuse potential, good for dull achy pain
Dextromethorphan - ✔✔Mu agonist, only works in lungs, low abuse
Heroin - ✔✔pro-drug opioid mu receptor agonist. Analgesia, euphoria, resp depression,
urinary retention, sedation. Converted to monoacetyl morphine/morphine in brain. Rapid
onset.
Diphenoxylate - ✔✔+ atropine, for diarrhea,
Diphenoxin - ✔✔+ atropine, for diarrhea
Loperamide - ✔✔Imodium, diarrhea
Pentazocine - ✔✔mixed agonist/antagonist. Kappa agonist, mu weak antagonist. Mild to
moderate pain
Buprenorphine - ✔✔PARTIAL mu agonist, used in tx of opoid abuse. Low abuse potential.
HIGH potency.
Nalbuphine - ✔✔Potent Kappa agonist and MU ANTAGONIST! Used for pain, less respiratory
effects, less abuse potential.
Butorphanol - ✔✔Partial opioid agonist, causing less respiratory effects. Bad for people with
opioid addiction. Mu.
Naloxone - ✔✔INactive orally. Very smart...mixed with opoids PO to stop IV abuse! Injection
only. Opioid antagonist. Short acting.
