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NURS 5334 Adv. Pharmacotherapeutics, Final Review questions with answers
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NURS 5334 Adv. Pharmacotherapeutics, Final Review questions with answers
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NURS 5334 Adv. Pharmacotherapeutics,Final Review questions with answers
Why ,,do ,,many ,,medications ,,lack ,,pediatric ,,dosing ,,information ,,in ,,their ,,drug ,,labeling?
A. ,,Most ,,medications ,,are ,,not ,,used ,,in ,,pediatric ,,patients. ,,
B. ,,There ,,is ,,a ,,lack ,,of ,,evidence-based ,,literature ,,on ,,the ,,safe ,,and ,,effective ,,use ,,of ,,medications ,,in
,,children.
C. ,,The ,,FDA ,,does ,,not ,,allow ,,pediatric ,,dosing ,,information ,,in ,,product ,,labeling. ,,
D. ,,Only ,,products ,,available ,,as ,,oral ,,liquid ,,formulations ,,are ,,required ,,to ,,contain ,,pediatric ,,dosing
,,information ,,in ,,their ,,labeling. ,,- ,,ANSWER: ,, ,,➡ ,,B. ,,There ,,is ,,a ,,lack ,,of ,,evidence-based ,,literature ,,on ,,the
,,safe ,,and ,,effective ,,use ,,of ,,medications ,,in ,,children.
Why ,,are ,,Neonates ,,at ,,greater ,,risk ,,for ,,toxicity ,,with ,,highly ,,protein-bound ,,drugs? ,,
A. ,,Protein ,,binding ,,is ,,decreased ,,in ,,neonates ,,increasing ,,the ,,amount ,,of ,,free ,,drug ,,available. ,,
B. ,,The ,,protein-bound ,,drugs ,,are ,,not ,,eliminated ,,effectively ,,in ,,neonates. ,,
C. ,,Neonates ,,are ,,unable ,,to ,,metabolize ,,these ,,highly ,,protein-bound ,,drugs. ,,
D. ,,Protein ,,binding ,,is ,,increased ,,in ,,neonates, ,,making ,,measurement ,,of ,,serum ,,levels ,,of ,,the ,,drug
,,inaccurate. ,,- ,,ANSWER: ,, ,,➡ ,,A. ,,Protein ,,binding ,,is ,,decreased ,,in ,,neonates ,,increasing ,,the ,,amount ,,of ,,free
,,drug ,,available.
At ,,what ,,age ,,are ,,adult ,,levels ,,of ,,renal ,,function ,,achieved? ,,•
A. ,,6 ,,months ,,
B. ,,12 ,,months ,,
C. ,,24 ,,months ,,
D. ,,3 ,,years ,,old ,,- ,,ANSWER: ,, ,,➡ ,,B. ,,12 ,,months
What ,,is ,,the ,,list ,,that ,,identifies ,,drugs ,,with ,,a ,,high ,,likelihood ,,of ,,causing ,,adverse ,,effects ,,in ,,the ,,elderly? ,,
A. ,,No ,,use ,,list ,,
B. ,,Beers ,,list ,,
, C. ,,Pharmacists ,,list ,,
D. ,,Adverse ,,drug ,,list ,,- ,,ANSWER: ,, ,,➡ ,,B. ,,Beers ,,list
In ,,pediatric ,,patients ,,gastric ,,acidity ,,does ,,not ,,reach ,,adult ,,values ,,for ,,______ ,,- ,,ANSWER: ,, ,,➡ ,,2 ,,Years
The ,,principles ,,underlying ,,complication ,,to ,,drug ,,therapy ,,in ,,the ,,elderly ,,include___, ,,____, ,,____, ,,and
,,____. ,,- ,,ANSWER: ,, ,,➡ ,,altered ,,pharmacokinetics, ,,multiple ,,and ,,severe ,,illnesses, ,,multiple-drug ,,therapy,
,,and ,,poor ,,adherence.
Altered ,,absorption ,,of ,,drugs ,,in ,,the ,,elderly ,,may ,,result ,,in____drug ,,response ,,- ,,ANSWER: ,, ,,➡ ,,Delay
The ,,four ,,major ,,factors ,,that ,,can ,,alter ,,drug ,,distribution ,,in ,,the ,,elderly ,,include ,,_, ,,_, ,,_, ,,and ,,_? ,,-
,,ANSWER: ,, ,,➡ ,,increased ,,body ,,fat, ,,decreased ,,percentage ,,of ,,lean ,,body ,,mass, ,,decreased ,,total ,,body
,,water, ,,and ,,reduced ,,concentration ,,of ,,serum ,,albumin.
The ,,most ,,important ,,cause ,,of ,,adverse ,,drug ,,reactions ,,in ,,the ,,elderly ,,is___. ,,- ,,ANSWER: ,, ,,➡ ,,drug
,,accumulation ,,secondary ,,to ,,reduced ,,renal ,,excretion.
In ,,the ,,elderly, ,,the ,,proper ,,index ,,of ,,renal ,,function ,,is____. ,,- ,,ANSWER: ,, ,,➡ ,,creatinine ,,clearance ,,or ,,GFR
Name ,,factors ,,underlying ,,the ,,increase ,,in ,,adverse ,,reactions ,,in ,,the ,,geriatric ,,population: ,,- ,,ANSWER: ,, ,,➡
,,• ,,Polypharmacy ,,
• ,,Severe ,,illness, ,,
• ,,multiple ,,pathologies, ,,
• ,,greater ,,use ,,of ,,drugs ,,that ,,have ,,a ,,low ,,therapeutic ,,index
• ,,Inadequate ,,supervision ,,
• ,,Poor ,,patient ,,adherence
What ,,is ,,maximum ,,amount ,,of ,,Sumatriptan ,,that ,,can ,,be ,,taken ,,in ,,1 ,,day? ,,
A. ,,100 ,,mg ,,
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