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Exam 2) NSG 533 Exam 2: Questions & Answers: Latest Updated: Guaranteed APlus Guide $7.99   Add to cart

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Exam 2) NSG 533 Exam 2: Questions & Answers: Latest Updated: Guaranteed APlus Guide

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when can an individual receive Serum HAV Ig for pre/post exposure prophylaxis? (Ans- pre: - <2 weeks before a trip - under 2 years old post: - up to 2 weeks post-exposure transmission of HBV (Ans- mucosal contact with infected blood or body fluid (saliva, semen) pathophysiology ...

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  • August 3, 2024
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NSG 533 Exam 2: Questions & Answers
when can an individual receive Serum HAV Ig for pre/post exposure
prophylaxis?
(Ans- pre:
- <2 weeks before a trip
- under 2 years old

post:
- up to 2 weeks post-exposure

transmission of HBV
(Ans- mucosal contact with infected blood or body fluid (saliva, semen)

pathophysiology of HBV
(Ans-
exposure to HBV --> cell-medicated immune response in cell nucleus -->
Cytotoxic T cells and NKC are sent to the virus to release inflammatory
cytokines --> initiation of inflammatory response --> HBV infiltrates
hepatocytes and replicates quickly

incubation period for HBV
(Ans- 60-150 days (average 90)

s/s acute HBV
(Ans- general illness (loss of appetite, fever, n/v)

s/s chronic HBV
(Ans- JAPSH

- jaundice
- ascites
- peripheral edema
- spider telangiectasias

,- hepatosplenomegaly

- positive serum test for 6 months

risk factors for HBV
(Ans-
- close contact
- hemodialysis
- IVDU
- tattoos (dye)

abnormal liver enzymes and serological markers for HBV (5)
(Ans-
1. HBsAg (marker of active disease)

2. IgM anti-HBc (recent infection <6months)

3. HBcAb Total (golden ticket for immunity)

4. HBsAb (surface antibody determines immunity from vaccination)

5. HBV DNA PCR Quantitative (viral load - how much viral is in the blood)

treatment of HBV
(Ans-
- medication (Tenofovir, Entacivir)

- PegIFN

- oral meds (only effective in chronic disease, stops viral repetition)

when to treat HBV
(Ans-
- viremia >2000
- fam hx of HCC

, - >40 years old
- ALT elevated more than 2x the upper limit
- liver biopsy

prevention of HBV
(Ans- vaccine, especially in hemodialysis patients

transmission of HCV
(Ans- infected blood

what are 80% of the new cases of HCV due to?
(Ans- PWID (people who inject drugs)

pathophysiology of HCV
(Ans- classified into 7 genotypes and several subtypes (1a and 1b cause
60% of cases)

can be acute or chronic

incubation period of HCV
(Ans- 2-22 weeks

s/s of HCV
(Ans- mostly asymptomatic until irreversible liver damage occurs

abnormal liver enzymes and serologic markers (5)
(Ans-
1. HCV Ab (only determines if you have been exposed)

2. HCV Ab w/ reflex PCR (best lab to order)

3. HCV RNA PCR Quantitative (tests for viral load)

4. HCV Genotype (used to characterize virus after diagnosis)

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