What is irritable bowel syndrome (IBS)? - ✔✔abdominal pain or discomfort that occurs in association
with altered bowel habits over a period of at least three months
How many IBS sufferers are women? - ✔✔2 out of 3
When does IBS peak? - ✔✔in the 3rd and 4th decades of life and declines in the 6th and 7th decades
Patients with IBS consume...more healthcare resources than those without it - ✔✔50%
What is IBS characterized by? - ✔✔changes in motility in response to environmental or enteric stimuli
...hypersensitivity is well documented in IBS patients - ✔✔visceral
It is believed that...plays a key role in IBS - ✔✔serotonin
What does serotonin do in IBS? - ✔✔-peripheral: motility modulating properties
-central: sensory modulating properties, could represent a common factor linking the symptoms of IBS
...inflammatory process may occur in IBS - ✔✔mucosal
What are signs and symptoms of IBS? - ✔✔-lower abdominal pain
-psychological symptoms such as depression and anxiety
, -reduced quality of life
What are non-GI symptoms of IBS? - ✔✔-urinary symptoms
-fatigue
-dyspareunia
What are some conditions associated with IBS? - ✔✔-fibromyalgia
-functional dyspepsia
-chronic fatigue syndrome
What are the different IBS subtypes? - ✔✔-diarrhea predominant (IBS-D)
-constipation predominant (IBS-C)
-alternating diarrhea and constipation
-pain predominant (IBS-P)
What is the Manning Criteria for diagnosing IBS? - ✔✔chronic or recurrent abdominal pain for at least 6
months and two or more of the following:
-abdominal pain relieved with defecation
-abdominal pain associated with more frequent stools
-abdominal pain associated with looser stools
-abdominal distension
-feeling of incomplete evacuation after defecation
-mucous in stools
What is the Rome III diagnostic criteria for IBS? - ✔✔recurrent abdominal pain or discomfort for at least
3 days per month in the last 3 months associated with two or more of the following:
-relieved with defecation
-onset associated with a change in frequency of stool
-onset associated with a change in form (appearance) of stool
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