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Androgen Pharmacology Exam Questions And Answers
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Androgen Pharmacology Exam Questions And Answers
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Androgen Pharmacology ExamQuestions And Answers
Testosterone synthesis -
correct answer ✅induced by LH
Normal serum testosterone:
Men:300-1000 ng/dL
Women: 30-50 ng/dL
metabolized in target tissues by 5alpha-reductase and aromatase to
active hormones DHT (dihydroxytestosterone) and estradiol
Indications for Androgen Replacement Therapy -
correct answer ✅Male hypogonadism: failure of testes to produce
androgen, sperm, or both; primary and secondary
Male delayed puberty
Androgen deficiency in adult men
Primary male hypogonadism -
correct answer ✅congenital; hypergonadotropic; high LH and FSH; low
testosterone
Klinefelter Syndrome
, Androgen Pharmacology Exam
Questions And Answers
Secondary hypogonadism -
correct answer ✅hypogonadotropic; low testosterone due to LH and
FSH
acquired or isolated gonadotropin deficiency
Klinefelter Syndrome -
correct answer ✅infertility an gynocomastia lead to diagnosis
Male delayed puberty -
correct answer ✅defective production of GnRH from hypothalamus
Testosterone therapy in adult men -
correct answer ✅make diagnosis of androgen deficiency only in men
wth consistent symptoms and signs and unequivocally low serum levels
Androgen Pharmacotherapies -
correct answer ✅esterification of 17-OH group produces long term IM
testosterone precursors; testosterone is not orally active
Testosterone Esters -
correct answer ✅IM administration; slowly absorbed and then rapidly
hydrolyzed in plasma to testosterone
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