Oxymetazoline (Actions/Uses) - Actions: activates alpha-adrenergic receptors in
sympathetic nervous system causing arterioles in nasal passage to constrict and dry
mucous membranes
Uses: Can be used in eyedrops but causes vasoconstriction of eye
Oxymetazoline (Admin Alerts) - Wash hands after administering to prevent anisocoria
(blurred visions and inequality of pupil size)
Oxymetazoline (Adverse Effects) - Rebound congestion common if used longer than 3-5
days
Minor stinging and dryness in nasal mucosa
Oxymetazoline (Contraindications) - Thyroid disorders, hypertension, or heart disease
Dextromethorphan (Adverse Effects) - Dizziness, drowsiness, and GI upset
If abused: CNS toxicity
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