NR 325 - Endocrine/Diabetes Class Notes-
Exam 1
Cushing's Disease - ANS-- Pituitary Tumor
- Increased ACTH, cortisol, urine free cortisol and plasma cortisol
Hypophysectomy - ANS-- removal of the pituitary (cure of cushing's disease)
-transphenoidal approach (no incision, through nose)
Cushing's Syndrome - ANS-- caused by drugs or adrenal issue
- only difference is the ACTH is low
Cushing's Treatment - ANS-- low fluid and sodium intake
- may need calcium, brittle bones
- if you aren't removing (treat symptoms)
Addison's - ANS-- corticosteroid insufficiency
- symptoms because body is slowing down
Primary Addison's - ANS-- damage to the adrenal gland
- 90% may be destroyed before you see symptoms
- have ACTH but missing corticosteroids
- pigmentation
- decreased plasma cortico's, free cortisol urine, serum cortisol
Secondary Addison's - ANS-- pituitary problem, or they stopped taking meds
- have nothing, no ACTH
Addison's: Medication - ANS-Hydrocortisone - has salt and sugar
Fludrocortisone - has minerals
Potassium: Cushing's and Addison's - ANS-C - need potassium
A - too much potassium
Adrenal Crisis - ANS-body is completely shutting down due to untreated addison's
Stress: Addison's - ANS-cannot make the cortisol to respond to stressful situations, may
need to increase medications when stressed
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