BIOD 210 genetics module 4 exam Latest Update
2024-2025 Actual Exam 150 Questions and 100%
Verified Correct Answers Guaranteed A+
_____________ are complexes where, among other activities, a great deal of RNA
degradation takes place. - CORRECT ANSWER: P bodies
____________________act as intermediaries between
______________________________ and specific _____ sequences to modify
chromatin structure and activate transcription. - CORRECT ANSWER: transcriptional
activators, chromatin-remodeling complex, DNA
A _________ mutation changes a codon that specifies an amino acid into one that
terminates translation.
nonsense
reverse
silent
missense
neutral - CORRECT ANSWER: nonsense
A __________ is a DNA stretch of 180 bp that specifies a 60 amino acid homeodomain.
- CORRECT ANSWER: homeobox
A catabolite-activating protein (CAP) exerts _____________control over the lac operon.
- CORRECT ANSWER: positive
A class of mutations that results in multiple contiguous amino acid changes in proteins
is likely to be the following:
transition.
frameshift.
A conditional mutation is one that allows a mutant gene product to function normally
under the ________ condition, but to function abnormally under the ________
condition. Such mutations are especially useful for the study of ________ mutations.
restrictive; permissive; dominant
permissive; restrictive; dominant
dominant; recessive; semidominant
recessive; dominant; codominant
permissive; restrictive; lethal - CORRECT ANSWER: permissive, restrictive, lethal
A eukaryotic DNA sequence that affects transcription at distant promoters is called a(n)
________________. - CORRECT ANSWER: enhancer
A highly-methylated region of a chromosome that has become largely deactivated and
can be seen as dense-regions when viewed using electron microscopy. - CORRECT
ANSWER: heterochromatin
A mutant E. coli strain, grown under conditions that normally induce the lac operon,
does not produce ß-galactosidase. What is a possible genotype of the cells?
lacI+ lacP+ lacO+ lacZ+ lacY- lacA+
lacI+ lacP+ lacOc lacZ+ lacY+ lacA+
lacl+ lacP+ lacO+ lacZ+ lacY+ lacA+
lacI+ lacP- lacO+ lacZ+ lacY+ lacA+ - CORRECT ANSWER: lacI+ lacP- lacO+ lacZ+
lacY+ lacA+
A mutant E. coli strain, grown under conditions that normally induce the lac operon,
produces high amounts of ß-galactosidase. What is a possible genotype of the cells?
lacI+ lacP- lacO+ lacZ+ lacY+ lacA+
Alternative RNA splicing is a method that apparently evolved for the production of many
different polypeptides from the same pre-mRNA. Provide an example of alternative
splicing. - CORRECT ANSWER: human genome has 20-25,000 genes but over
100,000 proteins, beta-globin is an example shown on slides,
alternative splicing can give rise to many different mRNA molecules from one pre-mRNA
and therefore many different proteins which is why one gene can code for multiple
proteins
Alternative splicing is known to be important in the regulation of
the production of heat-shock elements.
the mammalian SV40 virus.
the metallothionein gene.
the lac operon in E. coli. - CORRECT ANSWER: mamalian SV40 virus
An example of a gene product encoded by a regulatory gene is
allolactose.
operator.
beta-galactosidase enzyme.
repressor protein. - CORRECT ANSWER: repressor protein
An insulator is also known as a(n) __________________ . - CORRECT ANSWER:
boundary element
, An operon is controlled by a repressor. When the repressor binds to a small molecule, it
binds to DNA near the operon. The operon is constitutively expressed if a mutation
prevents the repressor from binding to the small molecule.
negative inducible
negative repressible
positive inducible
positive repressible - CORRECT ANSWER: negative repressible
An operon is controlled by a repressor. When the repressor binds to a small molecule, it
binds to DNA near the operon. The operon is constitutively expressed if a mutation
prevents the repressor from binding to the small molecule.
positive repressible
negative inducible
positive inducible
negative repressible - CORRECT ANSWER: negative repressible
Approximately 5% of the cytosine residues are methylated in the genome of any given
eukaryote. In what way is DNA methylation related to genetic regulation? - CORRECT
ANSWER: There is an inverse relationship between the degree of methylation of
eukaryotic DNA and the degree of gene expression
Apurinic (and apyrimidinic) sites (AP sites) involve a spontaneous loss of
______________ in an intact double-helix DNA molecule - CORRECT ANSWER: purine
Assume that a new mutation occurs in the germ line of an individual. What finding would
suggest that the new mutation is dominant rather than recessive? - CORRECT
ANSWER: If dominant and if passed to the next generation, it would be expressed. New
recessive mutations are not normally expressed in the next generation unless, through
a combination with a like mutation from the other parent, they are homozygous.
Assume that you are working with a mutant, nutritionally deficient strain of Escherichia
coli and that you isolate "revertants," which are nutritional-normal. Describe, at the
molecular level, two possible causes for the "reversion to wild type." - CORRECT
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