Pharmacology Ch 47 (2) Lipid-Lowering Agents
- Begin a low-fat diet
- Walk regularly
Rationale: Decreasing dietary fat intake and instituting regular aerobic exercise will decrease weight,
increase cardiovascular health, and reduce risk factors of metabolic syndrome. - ✔✔A client with
metabolic syndrome is encouraged to implement nonpharmacologic measures improve his risk
factors. What do those non-pharmacologic measures include? (Select all that apply.)
Rationale: Overall, the most effective blood lipid profile for prevention or management of metabolic
syndrome and its sequelae is high HDL cholesterol, low LDL cholesterol, and low total cholesterol. A
low triglyceride level is also desirable. - ✔✔To effectively prevent or manage metabolic syndrome,
what should the desired blood lipid profile include? (Select all that apply.)
"atorvastatin 10 mg PO OD"
Rationale: Atorvastatin is normally administered PO 10 to 80 mg daily in a single dose. - ✔✔An older
adult client's most recent physical assessment and diagnostic workup reveal the presence of
dyslipidemia. The woman is a candidate for monotherapy with a statin, and she will soon begin
treatment with atorvastatin. The nurse should anticipate what prescription from the health care
provider?
"Take the thiazide diuretic about 1 hour before the colestipol."
Rationale: The absorption of thiazide diuretic can be decreased or delayed with colestipol, a bile acid
sequestrant. Therefore, the diuretic should be taken 1 hour before or 4 to 6 hours after the colestipol.
- ✔✔A client who is receiving colestipol is also taking a thiazide diuretic. Which instruction would be
most appropriate for the nurse to give?
"This is an expected adverse effect of the drug. It should subside in time."
Rationale: Large doses of nicotinic acid produce peripheral vasodilation, mostly in the cutaneous
vessels of the face, neck, and chest. Vasodilation results in flushing of the skin and is usually
transient. The vasodilation is due to the histamine release caused by the medication. A nurse would
never tell a client not to worry and to stop taking the medication, unless the prescriber told her to. The
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