Exam (elaborations)
2024 NR 565 PHARM MIDTERM EXAM WITH CORRECT ANSWERS
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2024 NR 565 PHARM MIDTERM EXAM WITH CORRECT ANSWERS
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2024 NR 565 PHARM MIDTERMEXAM WITH CORRECT
ANSWERS
mood stabilizers - CORRECT ANSWERS-drugs used to control mood swings in
patients with bipolar mood disorders
Lithium - CORRECT ANSWERS-Inhibits IP3 second messenger cascade, mood
stabilizer for bipolar
therapeutic range 0.6 to 1.5
causes congenital malformations
NSAIDS - CORRECT ANSWERS-medication that exerts analgesic and anti-
inflammatory actions
Treats fever, pain, rheumatoid arthritis, osteoarthritis, gout, dysmenorrhea,
tendinitis
Aspirin - CORRECT ANSWERS-Antiplatelet for theumatic fever, tias, coronary
artery disease, DVT, decrease MI, fever, mild pain
can cause stomach irritation/ulcer, do not give to children with
flu-like/chicken pox because of reye syndrome
CYP2D6 - CORRECT ANSWERS-Need to increase doses of SSRI, beta blockers
etc.
Codeine can be deadly
CYP2C9 - CORRECT ANSWERS-Decrease warfarin dose
Test for gene VCORC1 mutation
CYP3A4 - CORRECT ANSWERS-Decreases elimination
Increase toxicity of Amio
Valproates - CORRECT ANSWERS-Blocks GABA uptake, treats seizures,
mania, bipolar, manic depressive
, SE: alopecia, drosiness, heartburn
Valproic acid or V P A, Depakote, Depakene
nonclassified mood stabilizers - CORRECT ANSWERS-nonbenzodiazepine
gaba-ergics that help treat epilepsy and bipolar, all effect GABA somehow
risk for kidney stones and steens-johnson syndrome (rash)
lamotrigine (Lamictal, gabapentin (Nuerontin) and topiramate (Topamax)
Centrally acting muscle relaxants - CORRECT ANSWERS-Relieves skeletal
muscle spasm in: spinal cord injury, multiple sclerosis, cerebral palsy
sedative effect, serotonin syndrome possible, do not take with MAO inhibitors
cyclobenzaprine, methocarbamol, baclofen, carisoprodol, chloraxazone
Direct-acting antispasmotics - CORRECT ANSWERS-Treats spasticity with
upper neuron disorders, spinal cord injury, stroke, cerebral palsy, ms
effects calcium, botox inhibits acetylcholine release
dantrolene titrated specially, no CNS depressing drugs, botox can have
deadly respiratory response
Dantroline sodium (Dantrium), botulinum toxin type A (Botox)
Opioid Analgesics and Antagonists - CORRECT ANSWERS-synthetic drugs that
bind to opiate receptors to relieve pain
SE of these drugs include dependence, withdrawal syndrome, sedation,
euphoria, respiratory depression nausea and vomiting, constipation
codeine, fentanyl, morphine, oxycodone, naloxone, etc.
Stimulants - CORRECT ANSWERS-Drugs (such as caffeine, nicotine, and the
more powerful amphetamines, cocaine, and Ecstasy) that excite neural
activity and speed up body functions
treat ADD/ADHD
SE: insomnia, anorexia,
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