GMS EXAM 1 ACTUAL QUESTIONS AND ANSWERS 2024 RATED A
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GMS
GMS EXAM 1 ACTUAL QUESTIONS AND ANSWERS 2024 RATED A
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GMS EXAM 1 ACTUAL QUESTIONS AND ANSWERS 2024
RATED A
Shared feature among Coronaviruses? Ans- They all produce a
nested set of subgenomic mRNAs.
True or False: The HE spike of coronaviruses is responsible for
fusion of the viral and host membranes. Ans- False
True or False: Coronaviruses bud at the plasma membrane. Ans- False
Where do CoV bud? Ans- in intermediate compartments (IC) within the
cell
True or False: Acute respiratory distress during a SARS infection is
likely caused by a cytokine storm. Ans- True
What is the accepted reservoir host of SARS? Ans- Bats
Which of the following viruses is not a member of the Flaviviridae
family?
1. Rotavirus
2. Yellow Fever Virus
3. West Nile Virus
4. Hep C Virus Ans- Rotavirus
,Shared feature between flaviviruses and togaviruses? Ans-
Many viruses in both families are arboviruses.
Which of the following statements about viral fusion is incorrect?
- The low pH of the endosome induces a conformational change
in the virion that exposes the fusion peptide.
,- The viral fusion glycoprotein is always the same glycoprotein that binds
the host receptor.
- Afterfusion of the viral membrane with the endosomal membrane,
the viral genome is released into the cytoplasm. Ans- The viral fusion
glycoprotein is always the same glycoprotein that binds the host
receptor.
Flaviviruses and togaviruses both generate polyproteins that thread into
and out of the ER membrane; what is the main purpose of this? Ans-
To localize the viral glycoproteins in the ER lumen where they can
then move to the Golgi and become glycosylated.
Which feature of togavirus/alphavirus virions is incorrect?
A- They have flower-shaped spikes extending off of the surface.
B- The envelope is icosahedral, but the capsid is disorganized.
C- Each petal associates with one capsid protein underneath the lipid
bilayer.
D- Each petal of the flower is comprised of a heterodimer of the two
glycoproteins (E1 and E2). Ans- The envelope is icosahedral, but the
capsid is disorganized.
What recruits host translation initiation factors to the 5' end of
calicivirus genomes? Ans- The
viral VPg protein
How are the norovirus structural proteins synthesized? Ans- They are
translated from a subgenomic mRNA produced late in the replication
cycle.
, Which of the following features is true
regarding norovirus virions? A- The minor
structural protein VP2 resides only inside the
virion.
B- They are extremely stable over a broad pH range.
C- The tips of the arches protruding off the surface are the most
hypervariable region of the virion.
D- All of these Ans- All of these
What are 3 features of Norovirus virions? Ans- 1. They are extremely
stable over a broad pH range.
2. The
tips of the arches protruding off the surface are the most
hypervariable region of the virion.
3. The minor structural protein VP2 resides only inside the virion.
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