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MCB4304 Exam 1 Questions & Answers 2024/2025

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MCB4304 Exam 1 Questions & Answers 2024/2025 What are some "big" questions concerning genomics and the information encoded in the human genome? - ANSWERS- to what extent are we determined by our genes? - are we defined by our genes or their expression? - how are physiology and health connect...

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  • August 6, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MCB4304
  • MCB4304
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MCB4304 Exam 1 Questions & Answers
2024/2025

What are some "big" questions concerning genomics and the information encoded in the human
genome? - ANSWERS- to what extent are we determined by our genes?

- are we defined by our genes or their expression?

- how are physiology and health connected to our genetic make-up?

- how do genes influence human behavior and thought patterns?



In addition to the "Central Dogma", what are some recent relevant emerging topics? - ANSWERS- are we
genetically programmed for susceptibility to advertisement (propaganda)?

- Why is belief so powerful?

- Are we evolutionarily adaptive?



What is a clear definition of "risk"? - ANSWERS- potential hazard + exposure = risk

- risk is a function of [hazard][exposure]



What are three hallmarks of "science"? - ANSWERS- embraces criticism

- uses rigorous repeatable methods

- changes with new evidence



What are three hallmarks of "pseudoscience"? - ANSWERS- grandiose claims that go beyond the
evidence

- uses vague jargon to confuse and evade

- uses inconsistent and invalid logic



What is an allele? - ANSWERSa different form a gene

, What is a gene variant? - ANSWERSoccurs when one allele is dominant over the other recessive allele



What is an open reading frame (ORF)? - ANSWERSthe sequence region within mRNA that can be
translated into protein



What is recombination? - ANSWERS- the rearrangement of genetic material, especially by crossing over
in chromosomes

- new combinations of alleles not seen in either parent



What is the relationship between genetic linkage and recombination? - ANSWERS- genetic linkage is not
absolute

- the closer genes are to one another increases the likelihood of recombination events



Why would an insertion or deletion in a gene ORF typically be more destructive than a point mutation? -
ANSWERS- the entire sequence is shifted on single insertions or deletions

- insertion/deletion of 3 base pairs does not disrupt the sequence and it can be repaired



What are the three domains of life? - ANSWERS- bacteria

- archaea

- eukarya



What are the four different bases found in DNA? - ANSWERS1. cytosine

2. guanine

3. adenine

4. thymine



What distinguishes RNA from DNA? - ANSWERS- RNA uses uracil instead of thymine

- RNA has self folding capabilities

- RNA made from ribose sugar

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