Genetics Final Exam|| 150 Questions & Answers|| 100% Accurate
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Course
Genetics
Institution
Genetics
Genetics Final Exam|| 150 Questions & Answers|| 100% AccurateGenetics Final Exam|| 150 Questions & Answers|| 100% AccurateGenetics Final Exam|| 150 Questions & Answers|| 100% AccurateGenetics Final Exam|| 150 Questions & Answers|| 100% Accurate
Two types of post-transcriptional modifications that ...
Genetics Final Exam||
150 Questions &
Answers|| 100%
Accurate
Genetics Final Exam|| 150
Questions & Answers||
100% Verified
,What modification neutralizes the charges on histones and looses up the interactions between histones
and DNA? - ANSWER ACETYLATION
Two types of post-transcriptional modifications that take place in the mRNA of eukaryotes - ANSWER the
addition of a CAP at the 5' end of the transcript and the addition of a POLY A sequence at the 3' end of
the message
Nucleic acid blotting is widely used in recombinant DNA technology. In a Southern blot one generally -
ANSWER Hybridizes filter-bound DNA with DNA probe
Assembly of basal transcription factors begins at the _______ sequence in the promoter. - ANSWER TATA
or "TATA box"
All of the following may result from promoter mutations except:
(A) Decreased affinity for RNA polymerase
(B) Increased affinity for RNA polymerase
(C) Mutant RNA polymerase
(D) Unregulated transcription
(E) A new phenotype - ANSWER (C) Mutant RNA polymerase
Imprinting is DNA modification in gametogenesis that effects gene expression in the zygote. - ANSWER
Occurs in the GERM line, accompanied by HEAVY METHYLATION. Once imprinted on, a SILENCED gene
remains inactivated during EMBRYOGENESIS.
Consider a eukaryotic transcriptional activator protein that binds to an enhance sequence and promotes
transcription. What change in regulation would you expect from a duplication in which several copies of
the enhancer were present instead of just one? - ANSWER INCREASED TRANSCRIPTION
Which of the following enzymes synthesizes DNA from a single stranded RNA template?
A genetic characteristic often associated with mutations caused by insertion of a transposable element is
________. - ANSWER (B) INSTABILITY ****add definition
Ultraviolet light primarily damages DNA by - ANSWER forming PYRIMIDINE dimers
A chromosome in which linear order of a group of genes is the reverse of normal order has an - ANSWER
INVERSION ***add definition
The F factor qualifies as an episome because it - ANSWER can exist either SEPARATE from the
chromosome or INCORPORATED into it
In a mating between Hfr and F- cells, the F- recipient - ANSWER REMAINS F-
Identify labeled part (A) of a typical eukaryotic gene and give a brief description of its function. -
ANSWER (A) ENHANCER: enhancer elements are bound by transcription factors (TF) or transcriptional
activators. Enhancers work upstream or downstream of the promoter, in either orientation, and from far
away the activation domain of the TF will interact with the basal transcription machinery including RNA
polymerase and increase the amount of txn from a promoter.
Identify labeled part (B) of a typical eukaryotic gene and give a brief description of its function. -
ANSWER (B) TATA BOX: A DNA sequence at which RNA polymerase binds and initiates transcription in
eukaryotes the highly conserved sequence is the TATA box.
Identify labeled part (C) of a typical eukaryotic gene and give a brief description of its function. -
ANSWER (C) EXONS: the sequences in a gene that are retained in the mRNA even after introns are
removed (to code for the final product).
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