Mutations - Genetics 3333 Test Questions and Answers
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Mutations - Genetics 3333
Institution
Mutations - Genetics 3333
Mutations - Genetics 3333 Test Questions and Answers
Spontaneous Mutations - Answer-- Mistakes during replication or recombination
- Wrong nucleotide is inserted
- Too many nucleotides are inserted or deleted
Tautomeric Shift - Answer-Rearrangement of bonds in a base so that its H bonding po...
Mutations - Genetics 3333 Test
Questions and Answers
Spontaneous Mutations - Answer-- Mistakes during replication or recombination
- Wrong nucleotide is inserted
- Too many nucleotides are inserted or deleted
Tautomeric Shift - Answer-Rearrangement of bonds in a base so that its H bonding
potential changes
Induced Mutations - Answer-A mutagen damages the DNA
- Damage causes a base to change its H bonding
- The mistake in base pairing is passed to progeny cells
- Ex: UV light, Ionizing radiation, base modifying agents, base analogs, and intercalating
agents
Base Pair Substitutions - Answer-Change from one base pair to another base pair
(replace a letter)
Base pair insertions/deletions - Answer-Addition or removal of a base pair (like you add
or remove a letter)
Transition Mutation - Answer-Change from purine to purine or pyrimidine to pyrimidine
Transversion mutation - Answer-Change from a purine to a pyrimidine or vise versa
Silent Mutation - Answer-A.K.A. Synonymous Mutation
- Codon is altered, but still codes for the same A.A. thanks to degeneracy
Missense Mutation - Answer-A change in a codon so that a different amino acid is
added to the polypeptide
- Phenotype depends on the severity of mutation
Nonsense Mutation - Answer-A sense codon to _______ codon (A.K.A Stop Codon)
- Usually degraded mRNA
- Premature termination of translation
- Results in truncated polypeptide
- Often results in null allele
Cause Frameshift Mutation - Answer-Shift in reading frame so that a missense or stop
results (by adding or subtracting)
- Usually, null allele and severe phenotype change, but depends where mutation occurs
in the coding sequence
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