Test Bank For Cellular and Molecular
Immunology, 10th Edition by Abul K.
Abbas, Andrew H. Lichtman,
APCs are... - ✔✔ANSW✔✔..antigen
presenting cells
MHC restriction is... - ✔✔ANSW✔✔..the
phenomenon that a T cell only recognizes a
specific peptide when that is displayed on
one specific type of MHC
Selectins and selectin ligands on
leukocytes include... - ✔✔ANSW✔✔..1)
Sialylated carbohydrate groups (including
Lewis A and X).
2) P-selectin glycoprotein ligand 1 (PSGL-
1)
, 3) L-selectin (CD62L) -> ensures homing to
lymph nodes
Selectins are... -
✔✔ANSW✔✔.....membrane carbohydrate-
binding adhesion molecules that mediate
the initial step of low-affinit adhesion of
circulating leukocytes to endothelial cells.
Selectins bind... - ✔✔ANSW✔✔.....
carbohydrate structures in a calcium-
dependent manner.
Selectins on endothelial cells include... -
✔✔ANSW✔✔..E- and P-selectins
The main responses of the innate immune
system are: - ✔✔ANSW✔✔..1)
inflammation (via leukocytes and plasma
proteins)
2) anti-viral respones
3) activate the adaptive immune response
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