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Pharmacology Exam 1: Questions & Accurate Solutions
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Pharmacology Exam 1: Questions & Accurate Solutions
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Pharmacology Exam 1: Questions & Accurate SolutionsAlprazolam Right Ans - Xanax
Methylenedioxymethamphetamine (MDMA) Right Ans - ecstasy
Diazepam Right Ans - Valium
Aceteminophen Right Ans - Tylenol
Lorazepam Right Ans - Ativan
Phenobarbital Right Ans - Luminal
Benzodiazepines Right Ans - -pam, -lam, -barbital endings
Levothyroxine Right Ans - Synthroid
Glasdegib Right Ans - Daurismo
-treats AML
Becavizumab Right Ans - Avastatin
-treats recurrent glioblastoma
Gabapentin Right Ans - Neurontin
-treats chronic pain
Fluoxetine Right Ans - Prozac
-treats depression and chronic pain (SSRI)
Omeprazole Right Ans - Prilosec
-treats GI issues
Pseudoephedrine Right Ans - Sudafed
-used by crackheads
Atropine Right Ans - Motofen
,Pregabalin Right Ans - Lyrica
Lisdexamfetamine Right Ans - Vyvanse
ED50 Right Ans - Effective dose in 50% of the population
EC50 Right Ans - Concentration of the drug that produces 50% of maximal
effect in one person
TD50 Right Ans - toxic dose in 50% of the population
LD50 Right Ans - lethal dose for 50% of the population
TI (therapeutic index) Right Ans - the ratio of the amount of drug to
produce a therapeutic dose compared with the amount of drug that produces
a lethal dose; the farther apart the ED and the TD the safer the drug
The graph above shows the dose-response curves for the therapeutic and
toxic effects of a new drug (Drug B) in a group of individuals compared to a
standard of care drug that is currently being prescribed to patients (Drug A).
Both drugs are tested in the same group of individuals. For Drug B, the
therapeutic index is _______ than that of Drug A, meaning that adverse effects
produced by the drug will occur at ______ doses compared to Drug A. Right
Ans - smaller; smaller
Ideally drugs will be both effective and safe. Penicillin, for example, is an
antibiotic used to treat infections caused by susceptible bacteria, and is
virtually nontoxic even in large doses (except for people who are allergic to
it). This means that penicillin has a very ____________ value.
A) high TD50
B) high ED50
C) Low TD50
D) Low ED50 Right Ans - A
biotransformation Right Ans - chemical changes that take place in the drug
following administration
, Metabolism Right Ans - the chemical transformation of a drug to a
metabolite
Excretion Right Ans - the removal of a drug and its metabolites from the
body
Absorption Right Ans - movement of the drug into the bloodstream after
administration
Bioavailability Right Ans - the rate at and the extent to which a nutrient is
absorbed and used
-if there are more barriers for the drug to cross, the bioavailability will be
lower
Distribution Right Ans - delivering a drug from the bloodstream to the
tissues of the body
Prodrug Right Ans - An inactive drug dosage form that is converted to an
active metabolite by various biochemical reactions once it is inside the body.
Prodrugs (increase/decrease) bioavailability? Right Ans - increase
polar drugs are excreted
(true or false) Right Ans - true
facilitated diffusion Right Ans - process of diffusion in which molecules
pass across the membrane via a carrier molecule, this does not require any
energy expenditure
nonpolar drugs are excreted
(true or false) Right Ans - false, are reabsorbed and stay in system longer
Passive diffusion is when a drug travels across the cell membrane from an
area of ____________ concentration to an area of ____________ concentration.
A)high; high
B)high; low
C)Low; high
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