advantage of an insulin pen
~ already mixed, great if that is what your order is for
- This does not have to be refrigerated, can be stuck in purse and taken with
you
Type 2
~ can make receptors accept insulin
- Metformin
- Glycoside
metformin
~ o Causes a lot of GI distress so they...
✓~ Time it takes for half of the drug to be excreted
Ex.15 mg, half-life of 5 hours, how much is there 5 hours later? 7&1/2
drug excretion
✓~ - Saliva
- Breast milk
- Sweat
,- Feces
- Kidneys
- Liver in bile (some)
- Lungs
pharmacodynamics
✓~ The effect the drug has on the body
primary effect
✓~ Desired response of the drug
secondary effects
✓~ Desirable or undesirable
- Ex. Viagra
- Can be side effects
therapeutic index
, ✓~ The range of the medication from when it is beneficial to when it is toxic
- Narrow = very easy to get to a toxic level
o Ex. Digoxin*** (0.5 - 1.0)
What happens when someone with liver disease takes drug
✓~ accumulation in the body
Signs of allergic reaction to drug
✓~ - Rash
- Hives
- Shortness of breath
- Tongue can swell up
- Wheezing
agonist
✓~ - Stimulates the receptor
- Produces desired response
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