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NSG318 Topic 2 Questions And Answers $11.49   Add to cart

Exam (elaborations)

NSG318 Topic 2 Questions And Answers

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  • NSG318

people of European descent ~ poor metabolizers of antidepressants, anti psychotics, cardiovascular agents, and isoniazid which can lead to toxicity people of African descent ~ diminished therapeutic effects from beta blockers, Ace inhibitors and warfarin people of Latin American descent ...

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  • August 8, 2024
  • 19
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NSG318
  • NSG318
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NSG318 Topic 2 Questions
And Answers

What are the pharmacokinetic phases?


✓~ absorption

distribution


metabolism


excretion




absorption


✓~ movement of the drug from the GI tract into the bloodstream after administration




distribution


✓~ movement of drugs from circulation into body tissues




metabolism (biotransformation)

, ✓~ body chemically changes drugs to a form that can be excreted




excretion


✓~ elimination of drugs from the body




disintegration


✓~ breakdown of oral drug into small particles




dissolution


✓~ process of combining small drug particles with liquid to form a solution




What are the two components of passive transport?


✓~ diffusion and facilitated transport




diffusion


✓~ drugs movement across cell membrane from high to low concentration




facilitated transport

, ✓~ relies on a carrier protein to move drug from high to low concentration




active transport


✓~ REQUIRES ENERGY (ATP) and carrier substance (enzyme)




pinocytosis


✓~ cell carries drug across membrane by engulfing drug particles




What are the factors that affect absorption?


✓~ blood circulation

pain, stress


food texture, fat content, temperature


pH


route of administration




How do drugs move from the GI tract to the liver?


✓~ via the hepatic portal vein

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